Immuno-positron emission tomography (immunoPET) is a paradigm-shifting molecular
imaging modality combining the superior targeting specificity of monoclonal antibody (mAb) …

Inert and stable radiolabeling of monoclonal antibodies (mAb), antibody fragments, or
antibody mimetics with radiometals is a prerequisite for immuno-PET. While radiolabeling is …

The identification of molecular drivers of disease and the compelling rise of biotherapeutics
have impacted clinical care but have also come with challenges. Such therapeutics include …

Targeting of human epidermal growth factor type 2 (HER2) using monoclonal antibodies,
antibody-drug conjugates and tyrosine kinase inhibitors extends survival of patients with …

Diagnostic molecular images, obtained by positron emission tomography (PET), have
successfully functioned as sensitive tools for detecting and monitoring the treatment of …

Objectives 89 Zr-labelled proteins are gaining importance in clinical research in a variety of
diseases. To date, no clinical study has been reported that utilizes an automated approach …

Efficient methods to functionalize proteins are essential for the development of many
diagnostic and therapeutic compounds, such as fluorescent probes for …

Methods that provide rapid access to radiolabeled antibodies are vital in the development of
diagnostic and radiotherapeutic agents for PET or radioimmunotherapy. The human …

The use of radiolabeled antibodies, immunoglobulin fragments, and other proteins are an
increasingly important sector of research for diagnostic imaging and targeted radiotherapy in …

Molecular imaging using PET plays an important role for the diagnosis of different diseases.
Immuno-PET combines the utilization of PET radionuclides and antibodies/proteins/peptides …