Despite being considered primarily a mood disorder, major depressive disorder (MDD) is
characterized by cognitive and decision making deficits. Recent research has employed …

Major depressive disorder (MDD) and substance use disorders (SUDs) are prevalent,
disabling, and challenging illnesses for which new treatment options are needed …

A revision of the 2008 British Association for Psychopharmacology evidence-based
guidelines for treating depressive disorders with antidepressants was undertaken in order to …

Background Clear guidance for successive antidepressant pharmacological treatments for
non-responders in major depression is not well established. Method Based on the …

Abstract Treatment resistance to the antidepressive pharmacotherapy represents one of the
most important clinical challenges in the pharmacological management of unipolar …

Background Pharmacological augmentation is a recommended strategy for patients with
treatment-resistant depression. A range of guidelines provide advice on treatment selection …

Schizophrenia and major depression are associated with alterations in peripheral
inflammatory markers, and anti-inflammatory therapy has been proposed as a promising …

Advances in our understanding of the epigenetic mechanisms that control gene expression
in the central nervous system (CNS) and their role in neuropsychiatric disorders are paving …

Accumulating evidence regarding clinical, neurobiological, genetic, and environmental
factors suggests a bidirectional link between obesity and depressive disorders. Although a …

This multicenter, cross-sectional study with retrospective assessment of treatment response
evaluated the current prescription trends and pharmacological treatment strategies applied …