Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches
JGM Bessems, NPE Vermeulen - Critical reviews in toxicology, 2001 - Taylor & Francis
An overview is presented on the molecular aspects of toxicity due to paracetamol
(acetaminophen) and structural analogues. The emphasis is on four main topics, that is …
(acetaminophen) and structural analogues. The emphasis is on four main topics, that is …
Hyperbaric Oxygen Reduces Acetaminophen Toxicity and Increases HIF‐1α Expression
SD Salhanick, B Belikoff, D Orlow, D Holt… - Academic …, 2006 - Wiley Online Library
Objectives: To investigate the effect of hyperbaric oxygen (HBO2) on acetaminophen (APAP)‐
induced hepatotoxicity. The authors further evaluated the effects of APAP poisoning and …
induced hepatotoxicity. The authors further evaluated the effects of APAP poisoning and …
[图书][B] A molecular genetic and cellular characterization of the acetaminophen and selenium binding proteins
CL Navarro - 1996 - search.proquest.com
Liver cytotoxicity after acetaminophen (APAP, N-acetyl p-aminophenol) overdose has been
associated with binding of the reactive metabolite, N-acetylbenzoquinoneimine (NAPQI), to …
associated with binding of the reactive metabolite, N-acetylbenzoquinoneimine (NAPQI), to …
[引用][C] Механизмы гепатотоксичности парацетамола
АИ Венгеровский, АС Саратиков - Фармакология и токсикология, 1991 - elibrary.ru