[HTML][HTML] Biomarkers for pancreatic neuroendocrine neoplasms (PanNENs) management—an updated review

M Bocchini, F Nicolini, S Severi, A Bongiovanni… - Frontiers in …, 2020 - frontiersin.org
Pancreatic neuroendocrine tumors (PanNENs) are rare sporadic cancers or develop as part
of hereditary syndromes. PanNENs can be both functioning and non-functioning based on …

Germline genetic variability in pancreatic cancer risk and prognosis

M Gentiluomo, F Canzian, A Nicolini… - Seminars in cancer …, 2022 - Elsevier
Pancreatic cancer (PC), particularly its most common form, pancreatic ductal
adenocarcinoma (PDAC), is relatively rare but highly lethal. Knowledge about PC risk …

Therapy of metastatic pancreatic neuroendocrine tumors (pNETs): recent insights and advances

T Ito, H Igarashi, RT Jensen - Journal of gastroenterology, 2012 - Springer
Abstract Neuroendocrine tumors (NETs)[carcinoids, pancreatic neuroendocrine tumors
(pNETs)] are becoming an increasing clinical problem because not only are they increasing …

Unraveling molecular pathways of poorly differentiated neuroendocrine carcinomas of the gastroenteropancreatic system: A systematic review

DM Girardi, ACB Silva, JFM Rêgo, RA Coudry… - Cancer Treatment …, 2017 - Elsevier
Background Poorly differentiated neuroendocrine carcinomas (NECs) are rare and
aggressive tumors. Their molecular pathogenesis is still largely unknown, and consequently …

[HTML][HTML] The evolving (epi) genetic landscape of pancreatic neuroendocrine tumours

CP Pipinikas, AM Berner, T Sposito… - Endocrine-related …, 2019 - erc.bioscientifica.com
Neuroendocrine neoplasms (NENs) are a relatively rare group of heterogeneous tumours
originating from neuroendocrine cells found throughout the body. Pancreatic NENs …

[HTML][HTML] Neuroendocrine neoplasms: current and potential diagnostic, predictive and prognostic markers

AD Herrera-Martínez, LJ Hofland… - Endocrine-related …, 2019 - erc.bioscientifica.com
Some biomarkers for functioning and non-functioning neuroendocrine neoplasms (NENs)
are currently available. Despite their application in clinical practice, results should be …

[HTML][HTML] Liquid biopsy and preclinical tools for advancing diagnosis and treatment of patients with pancreatic neuroendocrine neoplasms

B Smolkova, A Kataki, J Earl, I Ruz-Caracuel… - Critical Reviews in …, 2022 - Elsevier
Pancreatic neuroendocrine neoplasms (pNENs) are rare cancers with broad challenges for
their management. The main clinical obstacles are the high rate of patients diagnosed at …

[HTML][HTML] D-type cyclins in development and disease

M Saleban, EL Harris, JA Poulter - Genes, 2023 - mdpi.com
D-type cyclins encode G1/S cell cycle checkpoint proteins, which play a crucial role in
defining cell cycle exit and progression. Precise control of cell cycle exit is vital during …

PML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cells

FTM Chang, JD McGhie, FL Chan… - Nucleic acids …, 2013 - academic.oup.com
We have previously shown that α-thalassemia mental retardation X-linked (ATRX) and
histone H3. 3 are key regulators of telomeric chromatin in mouse embryonic stem cells. The …

Pancreatic neuroendocrine neoplasms: updates on genomic changes in inherited tumour syndromes and sporadic tumours based on WHO classification

H Ishida, AK Lam - Critical Reviews in Oncology/Hematology, 2022 - Elsevier
Pancreatic neuroendocrine neoplasms (PanNENs) are the neuroendocrine neoplasms with
greatest rate of increase in incidence. Approximately 10% of PanNENs arise as inherited …