Background Over the last decades, various approaches have been explored to restore
sufficient β-cell mass in diabetic patients. Stem cells are certainly an attractive source of new …

Introduction: The role of pharmacotherapy in the management of patients with Zollinger–
Ellison syndrome (ZES) is often equated with the medical management of acid …

Purpose: We aimed to test whether α-internexin could be a molecular biomarker of tumor
aggressiveness and prognosis in pancreatic neuroendocrine tumors (PNETs). Patients and …

Neuroendocrine tumors (NETs) are a heterogenous group of tumors that originate from
neuroendocrine cells, mainly in the pancreas and the gastrointestinal and …

Gastroenteropancreatic neuroendocrine neoplasms are a rare, diverse group of
neuroendocrine tumors that form in the pancreatic and gastrointestinal tract, and often …

Zollinger‐Ellison syndrome (ZES) can occur without an accompanying inherited syndrome
(ie, sporadic ZES) or as part of the multiple endocrine neoplasia type 1 syndrome (MEN1) …

Pancreatic neuroendocrine tumors (PanNETs) are rare tumors; however, their incidence
greatly increases with age, and they occur more frequently among the elderly. They …

Objective Epigenetic changes contribute to pancreatic neuroendocrine tumor (PanNET)
development. Hypermethylation of promoter DNA as a cause of tumor suppressor gene …

Pancreatic neuroendocrine neoplasms include mainly well-differentiated neuroendocrine
tumors but also rare poorly differentiated neuroendocrine carcinomas. Molecular …

Single-cell profiling of circulating tumor cells (CTCs) as part of a minimally invasive liquid
biopsy presents an opportunity to characterize and monitor tumor heterogeneity and …