The evolving landscape of neuroendocrine tumors

EK Bergsland - Seminars in Oncology, 2013 - Elsevier
Neuroendocrine tumors (NET) encompass a heterogeneous group of tumors demonstrating
varied clinical behavior. The field has recently witnessed several important developments …

[HTML][HTML] RSUME is implicated in tumorigenesis and metastasis of pancreatic neuroendocrine tumors

Y Wu, L Tedesco, K Lucia, AM Schlitter, JM Garcia… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The factors triggering pancreatic neuroendocrine tumor (PanNET) progression are largely
unknown. Here we investigated the role and mechanisms of the sumoylation enhancing …

Morphological and immunohistochemical profile of pancreatic neuroendocrine neoplasms

Z Simtniece, A Vanags, I Strumfa, M Sperga… - Polish Journal of …, 2015 - termedia.pl
The study represents a comprehensive retrospective morphological and
immunohistochemical profiling of pancreatic neuroendocrine neoplasms (PNENs) in order …

Interaction between microRNA-181a and TNFAIP1 regulates pancreatic cancer proliferation and migration

P Zhang, Z Guo, R Hu, X He, X Jiao, X Zhu - Tumor Biology, 2015 - Springer
We investigated the role of microRNA 181a (miR-181a) and its downstream target tumor
necrosis factor, alpha-induced protein 1 (TNFAIP1) in pancreatic cancer regulation …

[HTML][HTML] The structure and function of NKAIN2-a candidate tumor suppressor

SC Zhao, BW Zhou, F Luo, X Mao… - International Journal of …, 2015 - ncbi.nlm.nih.gov
The deletion of chromosomal region 6q was commonly found in several types of human
cancers, although the tumor suppressor genes (TSGs) located within this genomic region …

Predictive factors for recurrence of differentiated thyroid cancer in patients under 21 years of age and a meta-analysis of the current literature

N Qu, L Zhang, Z Lu, Q Ji, S Yang, W Wei, Y Zhang - Tumor Biology, 2016 - Springer
The influence of predictors for recurrence in relation to recurrence-free survival was
analyzed retrospectively in differentiated thyroid cancer (DTC) patients under 21 years of …

The p53 network as therapeutic target in gastroenteropancreatic neuroendocrine neoplasms

F Briest, P Grabowski - Cancer treatment reviews, 2015 - Elsevier
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are heterogeneous and
especially the midgut tumors currently lack effective therapy options. Actionable driver …

High-density array comparative genomic hybridization detects novel copy number alterations in gastric adenocarcinoma

AD Seabra, TMT Araújo, FAR MELLO… - Anticancer …, 2014 - ar.iiarjournals.org
Aim: To investigate frequent quantitative alterations of intestinal-type gastric
adenocarcinoma. Materials and Methods: We analyzed genome-wide DNA copy numbers of …

All Together Now: Standardization of Nomenclature for Neuroendocrine Neoplasms across Multiple Organs

P Jafari, AN Husain, N Setia - Surgical Pathology Clinics, 2023 - surgpath.theclinics.com
Neuroendocrine neoplasms (NENs) span virtually all organ systems and exhibit a broad
spectrum of behavior, from indolent to highly aggressive. Historically, nomenclature and …

Upregulation of INS-IGF2 read-through expression and identification of a novel INS-IGF2 splice variant in insulinomas

LE Johannessen, I Panagopoulos… - Oncology …, 2016 - spandidos-publications.com
Fusion transcripts arising from the combination of exons residing on neighboring genes on
the same chromosome may give rise to chimeric or novel proteins. Such read-through …