[HTML][HTML] Microglia heterogeneity in the single-cell era
Microglia are resident immune cells in the central nervous system (CNS) that are capable of
carrying out prominent and various functions during development and adulthood under both …
carrying out prominent and various functions during development and adulthood under both …
[HTML][HTML] Microglia and monocytes in inflammatory CNS disease: integrating phenotype and function
AG Spiteri, CL Wishart, R Pamphlett, G Locatelli… - Acta …, 2022 - Springer
In neurological diseases, the actions of microglia, the resident myeloid cells of the CNS
parenchyma, may diverge from, or intersect with, those of recruited monocytes to drive …
parenchyma, may diverge from, or intersect with, those of recruited monocytes to drive …
Long‐COVID syndrome‐associated brain fog and chemofog: Luteolin to the rescue
TC Theoharides, C Cholevas, K Polyzoidis… - Biofactors, 2021 - Wiley Online Library
COVID‐19 leads to severe respiratory problems, but also to long‐COVID syndrome
associated primarily with cognitive dysfunction and fatigue. Long‐COVID syndrome …
associated primarily with cognitive dysfunction and fatigue. Long‐COVID syndrome …
[HTML][HTML] TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis
F Cignarella, F Filipello, B Bollman, C Cantoni… - Acta …, 2020 - Springer
Multiple sclerosis (MS) is an inflammatory, demyelinating, and neurodegenerative disease
of the central nervous system (CNS) triggered by autoimmune mechanisms. Microglia are …
of the central nervous system (CNS) triggered by autoimmune mechanisms. Microglia are …
[HTML][HTML] Potential implications of quercetin in autoimmune diseases
P Shen, W Lin, L Han, K Qin, Y Huang… - Frontiers in Immunology, 2021 - frontiersin.org
Autoimmune diseases are a worldwide health problem with growing rates of morbidity, and
are characterized by breakdown and dysregulation of the immune system. Although their …
are characterized by breakdown and dysregulation of the immune system. Although their …
The role of glial cells in multiple sclerosis disease progression
LM Healy, JA Stratton, T Kuhlmann… - Nature Reviews Neurology, 2022 - nature.com
Despite the development of highly effective treatments for relapsing–remitting multiple
sclerosis (MS), limited progress has been made in addressing primary progressive or …
sclerosis (MS), limited progress has been made in addressing primary progressive or …
Targeting microglial autophagic degradation in NLRP3 inflammasome-mediated neurodegenerative diseases
AG Wu, XG Zhou, G Qiao, LU Yu, Y Tang, LU Yan… - Ageing research …, 2021 - Elsevier
Neuroinflammation is considered as a detrimental factor in neurodegenerative diseases,
including Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD) …
including Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD) …
[HTML][HTML] The role of GPNMB in inflammation
M Saade, G Araujo de Souza, C Scavone… - Frontiers in …, 2021 - frontiersin.org
Inflammation is a response to a lesion in the tissue or infection. This process occurs in a
specific manner in the central nervous system and is called neuroinflammation, which is …
specific manner in the central nervous system and is called neuroinflammation, which is …
[HTML][HTML] Targeted complement inhibition at synapses prevents microglial synaptic engulfment and synapse loss in demyelinating disease
S Werneburg, J Jung, RB Kunjamma, SK Ha… - Immunity, 2020 - cell.com
Multiple sclerosis (MS) is a demyelinating, autoimmune disease of the central nervous
system. While work has focused on myelin and axon loss in MS, less is known about …
system. While work has focused on myelin and axon loss in MS, less is known about …
Mucosal-associated invariant T cells restrict reactive oxidative damage and preserve meningeal barrier integrity and cognitive function
Increasing evidence indicates close interaction between immune cells and the brain,
revising the traditional view of the immune privilege of the brain. However, the specific …
revising the traditional view of the immune privilege of the brain. However, the specific …