SPRDA: a link prediction approach based on the structural perturbation to infer disease-associated Piwi-interacting RNAs

K Zheng, XL Zhang, L Wang, ZH You… - Briefings in …, 2023 - academic.oup.com
Abstract piRNA and PIWI proteins have been confirmed for disease diagnosis and treatment
as novel biomarkers due to its abnormal expression in various cancers. However, the …

Machine learning strategies in microRNA research: bridging genome to phenome

S Daniel Thomas, K Vijayakumar, L John… - OMICS: A Journal of …, 2024 - liebertpub.com
MicroRNAs (miRNAs) have emerged as a prominent layer of regulation of gene expression.
This article offers the salient and current aspects of machine learning (ML) tools and …

A feature extraction method based on noise reduction for circRNA-miRNA interaction prediction combining multi-structure features in the association networks

XF Wang, CQ Yu, ZH You, LP Li… - Briefings in …, 2023 - academic.oup.com
Motivation A large number of studies have shown that circular RNA (circRNA) affects
biological processes by competitively binding miRNA, providing a new perspective for the …

AMDECDA: attention mechanism combined with data ensemble strategy for predicting CircRNA-disease association

L Wang, L Wong, ZH You… - IEEE Transactions on Big …, 2023 - ieeexplore.ieee.org
Accumulating evidence from recent research reveals that circRNA is tightly bound to human
complex disease and plays an important regulatory role in disease progression. Identifying …

DeepCMI: a graph-based model for accurate prediction of circRNA–miRNA interactions with multiple information

YC Li, ZH You, CQ Yu, L Wang, L Hu… - Briefings in …, 2024 - academic.oup.com
Recently, the role of competing endogenous RNAs in regulating gene expression through
the interaction of microRNAs has been closely associated with the expression of circular …

BCMCMI: a fusion model for predicting circRNA-miRNA interactions combining semantic and meta-path

MM Wei, CQ Yu, LP Li, ZH You… - Journal of Chemical …, 2023 - ACS Publications
More and more evidence suggests that circRNA plays a vital role in generating and treating
diseases by interacting with miRNA. Therefore, accurate prediction of potential circRNA …

Improving prediction of drug-target interactions based on fusing multiple features with data balancing and feature selection techniques

H Khojasteh, J Pirgazi, A Ghanbari Sorkhi - Plos one, 2023 - journals.plos.org
Drug discovery relies on predicting drug-target interaction (DTI), which is an important
challenging task. The purpose of DTI is to identify the interaction between drug chemical …

Identifying circRNA-miRNA interaction based on multi-biological interaction fusion

D Yao, L Nong, M Qin, S Wu, S Yao - Frontiers in Microbiology, 2022 - frontiersin.org
CircRNA is a new type of non-coding RNA with a closed loop structure. More and more
biological experiments show that circRNA plays important roles in many diseases by …

[PDF][PDF] KS-CMI: A circRNA-miRNA interaction prediction method based on the signed graph neural network and denoising autoencoder

XF Wang, CQ Yu, ZH You, Y Qiao, ZW Li, WZ Huang… - Iscience, 2023 - cell.com
Circular RNA (circRNA) plays an important role in the diagnosis, treatment, and prognosis of
human diseases. The discovery of potential circRNA-miRNA interactions (CMI) is of guiding …

Identification of circRNA‐disease associations via multi‐model fusion and ensemble learning

J Yang, X Lei, F Zhang - Journal of Cellular and Molecular …, 2024 - Wiley Online Library
Circular RNA (circRNA) is a common non‐coding RNA and plays an important role in the
diagnosis and therapy of human diseases, circRNA‐disease associations prediction based …