Discoid Lupus Erythematosus (DLE) is a chronic cutaneous disease of unknown etiology
and of immunoinflammatory origin that is characterized by inflammatory plaques and may …

Macrophage migration inhibitory factor (MIF) is a cytokine with key roles in inflammation and
cancer, which qualifies it as a potential drug target. Apart from its cytokine activity, MIF also …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
loss of upper and lower motor neurons. About 20% of familial ALS cases are caused by …

Non-small-cell lung carcinoma (NSCLC) is one of the most common forms of lung cancer,
and a leading cause of cancer death among human beings. There is an urgent demand for …

Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine expressed by different
cell types and exerting multiple biological functions. It has been shown that MIF may be …

Neuroblastoma (NB) is the most frequent solid tumor in pediatric cases, contributing to
around 15% of childhood cancer-related deaths. The wide-ranging genetic, morphological …

Proinflammatory cytokines are produced in pregnancy in response to the invading
pathogens and/or nonmicrobial causes such as damage-associated molecules and …

A number of emerging studies in field of immune metabolism have indicated that cellular
metabolic reprograming serves as a major administrator in maintaining the viability and …

Ultraviolet irradiation (UV) exposure is the leading factor underlying the development of skin
malignancies. D‐dopachrome tautomerase (D‐DT), a functional homolog of macrophage …

Discovered as inflammatory cytokines, MIF and DDT exhibit widespread expression and
have emerged as critical mediators in the response to infection, inflammation, and more …