The effect of palmitic acid on inflammatory response in macrophages: an overview of molecular mechanisms
J Korbecki, K Bajdak-Rusinek - Inflammation Research, 2019 - Springer
Palmitic acid is a saturated fatty acid whose blood concentration is elevated in obese
patients. This causes inflammatory responses, where toll-like receptors (TLR), TLR2 and …
patients. This causes inflammatory responses, where toll-like receptors (TLR), TLR2 and …
Dyslipidemia in obesity: mechanisms and potential targets
B Klop, JWF Elte, M Castro Cabezas - Nutrients, 2013 - mdpi.com
Obesity has become a major worldwide health problem. In every single country in the world,
the incidence of obesity is rising continuously and therefore, the associated morbidity …
the incidence of obesity is rising continuously and therefore, the associated morbidity …
Obesity and osteoarthritis, more than just wear and tear: pivotal roles for inflamed adipose tissue and dyslipidaemia in obesity-induced osteoarthritis
E Thijssen, A Van Caam, PM Van Der Kraan - Rheumatology, 2015 - academic.oup.com
OA is a degenerative joint disease characterized by articular cartilage degradation,
osteophyte formation, synovitis, and subchondral bone sclerosis. One of OAs main risk …
osteophyte formation, synovitis, and subchondral bone sclerosis. One of OAs main risk …
Metabolic syndrome and the lung
A link between metabolic syndrome (MetS) and lung diseases has been observed in several
cross-sectional and longitudinal studies. This syndrome has been identified as an …
cross-sectional and longitudinal studies. This syndrome has been identified as an …
[HTML][HTML] Palmitate activates the NF-κB transcription factor and induces IL-6 and TNFα expression in 3T3-L1 adipocytes
KM Ajuwon, ME Spurlock - The Journal of nutrition, 2005 - Elsevier
Fatty acids and their metabolites regulate gene expression and immunological pathways.
Furthermore, obese individuals frequently have increased circulating fatty acid …
Furthermore, obese individuals frequently have increased circulating fatty acid …
[HTML][HTML] Docosahexaenoic acid inhibits adipocyte differentiation and induces apoptosis in 3T3-L1 preadipocytes
HK Kim, MA Della-Fera, J Lin, CA Baile - The Journal of nutrition, 2006 - Elsevier
ABSTRACT Docosahexaenoic acid (DHA, C22: 6), a (n-3) fatty acid in fish oil, has been
shown to decrease body fat and fat accumulation in rodents. We investigated the direct effect …
shown to decrease body fat and fat accumulation in rodents. We investigated the direct effect …
Saturated fatty acids, obesity, and the nucleotide oligomerization domain–like receptor protein 3 (NLRP3) inflammasome in asthmatic patients
Background Both obesity and high dietary fat intake activate the nucleotide oligomerization
domain–like receptor protein 3 (NLRP3) inflammasome. Objective We aimed to examine …
domain–like receptor protein 3 (NLRP3) inflammasome. Objective We aimed to examine …
Obstructive sleep apnea dynamically increases nocturnal plasma free fatty acids, glucose, and cortisol during sleep
Context Obstructive sleep apnea (OSA) is associated with diabetes and cardiovascular
disease. This association may be related to metabolic changes that transpire during sleep in …
disease. This association may be related to metabolic changes that transpire during sleep in …
Mangiferin Improved Palmitate‐Induced‐Insulin Resistance by Promoting Free Fatty Acid Metabolism in HepG2 and C2C12 Cells via PPARα: Mangiferin Improved …
Q Zhang, X Kong, H Yuan, H Guan… - Journal of Diabetes …, 2019 - Wiley Online Library
Elevated free fatty acid (FFA) is a key risk factor for insulin resistance (IR). Our previous
studies found that mangiferin could decrease serum FFA levels in obese rats induced by a …
studies found that mangiferin could decrease serum FFA levels in obese rats induced by a …
The triglyceride and glucose index and risk of nonalcoholic fatty liver disease: A dose–response meta-analysis
Background The triglyceride and glucose (TyG) index is associated with the risk of
nonalcoholic fatty liver disease (NAFLD), but the dose− response relationship between them …
nonalcoholic fatty liver disease (NAFLD), but the dose− response relationship between them …