Evolution of the innate immune system: the worm perspective
H Schulenburg, C Léopold Kurz… - Immunological …, 2004 - Wiley Online Library
Simple model organisms that are amenable to comprehensive experimental analysis can be
used to elucidate the molecular genetic architecture of complex traits. They can thereby …
used to elucidate the molecular genetic architecture of complex traits. They can thereby …
'Ready made'virulence and 'dual use'virulence factors in pathogenic environmental fungi—the Cryptococcus neoformans paradigm
A Casadevall, JN Steenbergen… - Current Opinion in …, 2003 - Elsevier
Environmental pathogenic fungi present a paradox in that they are virulent in animals
without requiring animal hosts for replication or survival, a phenomenon we call 'ready …
without requiring animal hosts for replication or survival, a phenomenon we call 'ready …
Control of intestinal bacterial proliferation in regulation of lifespan in Caenorhabditis elegans
C Portal-Celhay, ER Bradley, MJ Blaser - BMC microbiology, 2012 - Springer
Background A powerful approach to understanding complex processes such as aging is to
use model organisms amenable to genetic manipulation, and to seek relevant phenotypes …
use model organisms amenable to genetic manipulation, and to seek relevant phenotypes …
Evaluation of probiotic characteristics of newly isolated Lactobacillus spp.: immune modulation and longevity
In the current study, the probiotic potential of approximately 350 strains of lactic acid bacteria
isolated from Korean infant feces and Kimchi was investigated. Common probiotic properties …
isolated from Korean infant feces and Kimchi was investigated. Common probiotic properties …
Molecular mechanisms of pathogenicity: how do pathogenic microorganisms develop cross-kingdom host jumps?
P Van Baarlen, A Van Belkum… - FEMS microbiology …, 2007 - academic.oup.com
It is common knowledge that pathogenic viruses can change hosts, with avian influenza, the
HIV, and the causal agent of variant Creutzfeldt–Jacob encephalitis as well-known …
HIV, and the causal agent of variant Creutzfeldt–Jacob encephalitis as well-known …
Mechanisms of resistance to oxidative and nitrosative stress: implications for fungal survival in mammalian hosts
TA Missall, JK Lodge, JE McEwen - Eukaryotic cell, 2004 - Am Soc Microbiol
The ability of a fungal pathogen to cause disease requires the ability to survive in the host.
Survival in the host is dependent on evasion of the host's immune system, including the …
Survival in the host is dependent on evasion of the host's immune system, including the …
Models of Caenorhabditis elegans infection by bacterial and fungal pathogens
JR Powell, FM Ausubel - Innate immunity, 2008 - Springer
The nematode Caenorhabditis elegans is a simple model host for studying the relationship
between the animal innate immune system and a variety of bacterial and fungal pathogens …
between the animal innate immune system and a variety of bacterial and fungal pathogens …
Antifungal Efficacy during Candida krusei Infection in Non-Conventional Models Correlates with the Yeast In Vitro Susceptibility Profile
L Scorzoni, MP de Lucas, AC Mesa-Arango… - PloS one, 2013 - journals.plos.org
The incidence of opportunistic fungal infections has increased in recent decades due to the
growing proportion of immunocompromised patients in our society. Candida krusei has …
growing proportion of immunocompromised patients in our society. Candida krusei has …
[HTML][HTML] The origin and maintenance of virulence for the human pathogenic fungus Cryptococcus neoformans
JN Steenbergen, A Casadevall - Microbes and infection, 2003 - Elsevier
The origin of virulence in environmental fungi that have no requirement for animal hosts in
their life cycle is enigmatic. Cryptococcus neoformans is a human pathogenic fungus with …
their life cycle is enigmatic. Cryptococcus neoformans is a human pathogenic fungus with …
[HTML][HTML] Specificity of the innate immune system and diversity of C-type lectin domain (CTLD) proteins in the nematode Caenorhabditis elegans
The nematode Caenorhabditis elegans has become an important model for the study of
innate immunity. Its immune system is based on several signaling cascades, including a Toll …
innate immunity. Its immune system is based on several signaling cascades, including a Toll …