Strategies for engineering of extracellular vesicles
AA Danilushkina, CC Emene, NA Barlev… - International journal of …, 2023 - mdpi.com
Extracellular vesicles (EVs) are membrane vesicles released by cells into the extracellular
space. EVs mediate cell-to-cell communication through local and systemic transportation of …
space. EVs mediate cell-to-cell communication through local and systemic transportation of …
Recent advances of exosomes in soft tissue injuries in sports medicine: A critical review on biological and biomaterial applications
Sports medicine is generally associated with soft tissue injuries including muscle injuries,
meniscus and ligament injuries, tendon ruptures, tendinopathy, rotator cuff tears, and tendon …
meniscus and ligament injuries, tendon ruptures, tendinopathy, rotator cuff tears, and tendon …
Forging new therapeutic targets: efforts of tumor derived exosomes to prepare the pre-metastatic niche for cancer cell dissemination and dormancy
Tumor-derived exosomes play a multifaceted role in preparing the pre-metastatic niche,
promoting cancer dissemination, and regulating cancer cell dormancy. A brief review of …
promoting cancer dissemination, and regulating cancer cell dormancy. A brief review of …
Biodistribution of mesenchymal stromal cell-derived extracellular vesicles administered during acute lung injury
A Tieu, DJ Stewart, D Chwastek, C Lansdell… - Stem Cell Research & …, 2023 - Springer
Background Mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) are a
promising cell-free therapy for acute lung injury (ALI). To date, no studies have investigated …
promising cell-free therapy for acute lung injury (ALI). To date, no studies have investigated …
Cellular Uptake of Engineered Extracellular Vesicles: Biomechanisms, Engineered Strategies, and Disease Treatment
Q Xie, Y Hao, N Li, H Song, X Chen… - Advanced …, 2024 - Wiley Online Library
Abstract Extracellular vesicles (EVs), lipid‐enclosed nanosized membrane vesicles, are
regarded as new vehicles and therapeutic agents in intercellular communication. During …
regarded as new vehicles and therapeutic agents in intercellular communication. During …
Extracellular vesicles as reconfigurable therapeutics for eye diseases: Promises and hurdles
A large number of people worldwide suffer from visual impairment. However, most available
therapies rely on impeding the development of a particular eye disorder. Therefore, there is …
therapies rely on impeding the development of a particular eye disorder. Therefore, there is …
Formation and Investigation of Cell‐Derived Nanovesicles as Potential Therapeutics against Chronic Liver Disease
AA Ganguin, I Skorup, S Streb… - Advanced healthcare …, 2023 - Wiley Online Library
A new therapeutic approach using cell‐derived nanovesicles (cdNVs) is offered here to
overcome the lack of effective treatments for liver fibrosis, a reversible chronic liver disease …
overcome the lack of effective treatments for liver fibrosis, a reversible chronic liver disease …
Extracellular vesicles as human therapeutics: A scoping review of the literature
C Fusco, G De Rosa, I Spatocco… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs) are released by all cells and contribute to cell‐to‐cell
communication. The capacity of EVs to target specific cells and to efficiently deliver a …
communication. The capacity of EVs to target specific cells and to efficiently deliver a …
Biological functions and biomedical applications of extracellular vesicles derived from blood cells
K Pan, Y Zhu, P Chen, K Yang, Y Chen, Y Wang… - Free Radical Biology …, 2024 - Elsevier
There is a growing interest in using extracellular vesicles (EVs) for therapeutic applications.
EVs are composed of cytoplasmic proteins and nucleic acids and an external lipid bilayer …
EVs are composed of cytoplasmic proteins and nucleic acids and an external lipid bilayer …
Physical modulation of mesenchymal stem cell exosomes: A new perspective for regenerative medicine
D Wu, X Zhao, J Xie, R Yuan, Y Li, Q Yang… - Cell …, 2024 - Wiley Online Library
Mesenchymal stem cell‐derived exosomes (MSC‐Exo) offer promising therapeutic potential
for various refractory diseases, presenting a novel therapeutic strategy. However, their …
for various refractory diseases, presenting a novel therapeutic strategy. However, their …