Aims To analyse the safety and efficacy of direct oral anticoagulants (DOACs) in real-world
studies including atrial fibrillation (AF) patients. Methods and results Systematic review and …

Background & Aims There is controversy over whether use of non-vitamin K antagonist oral
anticoagulants (NOACs) associates with increased risk of major gastrointestinal bleeding …

Importance Warfarin is prescribed to patients with atrial fibrillation (AF) for the prevention of
cardioembolic complications. Whether warfarin adversely affects bone health is …

Although known for its importance in the coagulation cascade, vitamin K has other functions.
It is an essential vitamin for bone health, taking part in the carboxylation of many bone …

Background and Purpose: Several observational studies have compared the effect of the
non–vitamin K antagonist oral anticoagulants to each other in patients with atrial fibrillation …

Background Oral anticoagulants (OACs) in patients with atrial fibrillation (AF), in addition to
reducing stroke risk, could also prevent adverse cognitive outcomes. The purpose of this …

Abstract Background Vitamin K antagonist (VKA) anticoagulant use is suspected to increase
the risk of bone fracture through inhibition of vitamin K–dependent cofactors of bone …

Older people, are underrepresented in randomised controlled trials of direct oral
anticoagulants (DOACs) for stroke prevention in atrial fibrillation (AF). The aim of this study …

Los anticoagulantes orales de acción directa (ACOD) son fármacos que han demostrado
tener un perfil de seguridad superior a los antivitamina K (AVK). En España la prescripción …

Background Patients with warfarin have a potential risk of warfarin-related nephropathy,
which could result in the discontinuation of anticoagulation therapy. The question of whether …