Mesenchymal stromal cells (MSCs) are currently being investigated for use in a wide variety
of clinical applications. For most of these applications, systemic delivery of the cells is …

Cardiovascular disease (CVD) is the leading cause of death worldwide. A search for more
effective treatments of CVD is increasingly needed. Major advances in nanotechnology …

During the past decades, stem cell-based therapy has acquired a promising role in
regenerative medicine. The application of novel cell therapeutics for the treatment of …

Stem cell therapy has emerged as a new strategy for treatment of ischemic heart disease.
Although umbilical cord-derived mesenchymal stromal cells (UC-MSCs) have been used …

The therapeutic efficacy of umbilical cord mesenchymal stem cells (UCMSCs) in acute
respiratory distress syndrome (ARDS) is mainly limited by the efficiency of homing of …

Aims Atherosclerosis is a chronic inflammatory disease of the vasculature. Mesenchymal
stem cells (MSCs) exert immunomodulatory and immunosuppressive effects by secreting …

Cardiac muscle cells have an innate capacity to perceive and react to mechanical strain via
a mechanism known as mechanotransduction, whereby the cardiac muscle cells are …

Cardiac matrix hydrogel has shown great promise as an injectable biomaterial due to the
possession of cardiac-specific extracellular matrix composition. A cardiac matrix hydrogel …

Over the past two decades cardiac cell therapy (CCT) has emerged as a promising new
strategy to cure heart diseases at high unmet need. Thousands of patients have entered …

Bone marrow-mesenchymal stem cell (BM-MSC) therapy improves the recovery of cardiac
function after myocardial infarction (MI); however, the underlying molecular mechanisms are …