The natural killer cell interferon-gamma response to bacteria is diminished in untreated HIV-1 infection and defects persist despite viral suppression

SM Dillon, EJ Lee, JM Bramante, E Barker… - JAIDS Journal of …, 2014 - journals.lww.com
Objective: Natural killer (NK) cells are important in innate immune responses to bacterial
and viral pathogens. HIV-1 infection is associated with opportunistic bacterial infections and …

Natural killer cell function is well preserved in asymptomatic human immunodeficiency virus type 2 (HIV-2) infection but similar to that of HIV-1 infection when CD4 T …

SV Nuvor, M van der Sande, S Rowland-Jones… - Journal of …, 2006 - Am Soc Microbiol
Natural killer (NK) cells are potent effectors of natural immunity and their activity prevents
human immunodeficiency virus type 1 (HIV-1) viral entry and viral replication. We sought to …

Restricted recruitment of NK cells with impaired function is caused by HPV-driven immunosuppressive microenvironment of Papillomas in aggressive juvenile-onset …

W Wang, Y Xi, S Li, X Liu, G Wang, H Wang… - Journal of …, 2022 - Am Soc Microbiol
Laryngopharynx epithelium neoplasia induced by HPV6/11 infection in juvenile-onset
recurrent respiratory papillomatosis (JO-RRP) causes a great health issue characteristic of …

Here today–not gone tomorrow: roles for activating receptors in sustaining NK cells during viral infections

SH Lee, CA Biron - European journal of immunology, 2010 - Wiley Online Library
The conclusive evidence supporting a role for NK cells in defense against viruses has been
obtained under conditions of NK cell deficiencies prior to infections. NK cell proliferation can …

[HTML][HTML] The putative role of natural killer cells in patients with hepatitis C virus-related hepatocellular carcinoma

MM Hassona, EM Radwan… - Asian Pacific Journal …, 2021 - ncbi.nlm.nih.gov
Background: Natural Killer (NK) cells have crucial roles in immune responses against
malignant transformation including hepatocellular carcinoma (HCC). The NKG2D receptor …

NK cells prevalence, subsets and function in viral hepatitis C

J Żeromski, I Mozer-Lisewska, M Kaczmarek… - Archivum immunologiae …, 2011 - Springer
Innate immunity appears to play an important role in the pathogenesis of viral hepatitis C.
Among various cell subsets of this immunity natural killer (NK) cells raised particular interest …

[HTML][HTML] Analysis of peripheral blood dendritic cells as a non-invasive tool in the follow-up of patients with chronic hepatitis C

A Crosignani, A Riva, S Della Bella - World journal of …, 2016 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) has a high propensity to establish chronic infections. Failure of HCV-
infected individuals to activate effective antiviral immune responses is at least in part related …

[HTML][HTML] PEG-IFN alpha but not ribavirin alters NK cell phenotype and function in patients with chronic hepatitis C

AA Markova, U Mihm, V Schlaphoff, S Lunemann… - PLoS …, 2014 - journals.plos.org
Background Ribavirin (RBV) remains part of several interferon-free treatment strategies
even though its mechanisms of action are still not fully understood. One hypothesis is that …

Liver cirrhosis in HIV/HCV‐coinfected individuals is related to NK cell dysfunction and exhaustion, but not to an impaired NK cell modulation by CD4+ T‐cells

ML Polo, YA Ghiglione, JP Salido… - African Journal of …, 2019 - journals.lww.com
2 Methods Healthy volunteers (HV, n= 20) and HIV/HCV‐coinfected individuals (n= 34) on
follow‐up at a Public Hospital Infectious Diseases Unit, Buenos Aires, Argentina, were …

Contradicting roles of miR-182 in both NK cells and their host target hepatocytes in HCV

SA El Sobky, NM El-Ekiaby, RY Mekky, NM Elemam… - Immunology …, 2016 - Elsevier
Background and aim Natural killer cells are part of the innate immunity involved in viral
eradication and were shown to be greatly affected by HCV infection. Epigenetic regulation of …