In the last decade, Chimeric Antigen Receptor (CAR)-T cell therapy has emerged as a
promising immunotherapeutic approach to fight cancers. This approach consists of …

Natural Killer (NK) cells and CD8+ cytotoxic T cells are two types of immune cells that can
kill target cells through similar cytotoxic mechanisms. With the remarkable success of …

The innate lymphoid cell (ILC) family is composed of natural killer (NK) cells, ILC1, ILC2 and
ILC3, which participate in immune responses to virus, bacteria, parasites and transformed …

Hepatocellular carcinoma (HCC) ranks the most common primary liver malignancy and the
third leading cause of tumor-related mortality worldwide. Unfortunately, despite advances in …

Natural killer (NK) cells play indispensable roles in innate immune responses against tumor
progression. To depict their phenotypic and functional diversities in the tumor …

Hepatocellular carcinoma (HCC) is a common malignancy, and the hepatitis B virus (HBV) is
its major pathogenic factor. Over the past decades, it has been confirmed that HBV infection …

Liver cancer has the fourth highest mortality rate of all cancers worldwide, with
hepatocellular carcinoma (HCC) being the most prevalent subtype. Despite great advances …

Background and aims Chronic inflammation induced by chronic hepatitis B virus (HBV)
infection increases the risk of hepatocellular carcinoma (HCC). However, little is known …

Immune checkpoint blockade has become a promising therapeutic approach to reverse
immune cell exhaustion. Coinhibitory CD96 and T‐cell immunoglobulin and ITIM domain …

Natural killer (NK) cells can induce an antigen-independent immune response against
malignant cells. A growing number of scientific reports and clinical studies have shown …