Quinoline derivatives volunteering against antimicrobial resistance: rational approaches, design strategies, structure activity relationship and mechanistic insights

N Kumar, A Khanna, K Kaur, H Kaur, A Sharma… - Molecular Diversity, 2023 - Springer
Emergence of antimicrobial resistance has become a great threat to human species as there
is shortage of development of new antimicrobial agents. So, its mandatary to combat AMR …

Repurposing bedaquiline for effective non-small cell lung cancer (NSCLC) therapy as inhalable cyclodextrin-based molecular inclusion complexes

V Parvathaneni, RS Elbatanony, M Goyal… - International journal of …, 2021 - mdpi.com
There is growing evidence that repurposed drugs demonstrate excellent efficacy against
many cancers, while facilitating accelerated drug development process. In this study …

The potential of 2-substituted quinolines as antileishmanial drug candidates

PM Loiseau, K Balaraman, G Barratt, S Pomel… - Molecules, 2022 - mdpi.com
There is a need for new, cost-effective drugs to treat leishmaniasis. A strategy based on
traditional medicine practiced in Bolivia led to the discovery of the 2-substituted quinoline …

Ultrasound assisted synthesis of hybrid quinoline anchored with 4-R-benzenesulfonamide moiety with potential antimicrobial activity

D Diaconu, V Mangalagiu, S Dunca… - Heliyon, 2023 - cell.com
We present in this paper a direct and efficient study regarding synthesis and spectral
characterization of three series of hybrid quinoline anchored with 4-R-benzenesulfonamide …

[PDF][PDF] Identification of Suitable Agents against Adenine Phosphoribosyl Transferase for the Management of Leishmaniasis: Synthesis, Characterization and …

R Sharma, D Yadav, R Yadav - Biointerface Res Appl …, 2022 - biointerfaceresearch.com
A leishmaniasis is a group of diseases attributable to protozoan parasites of the genus
Leishmania. It is a potential disease mostly occurring in developing nations. Various …

Synthesis and X-ray structure of the first thioether of quinolin-2-one naming as 4, 4'-thio-bis (1-methylquinoline-2 (1H)-thione) and X-ray structure of 3, 3'-methylenebis …

BAA Balboul, AA Aly, O Fuhr, EM Osman… - 2023 - researchsquare.com
Synthesis and X-ray structure analysis of 4, 4'-thiobis (1-methylquinoline-2 (1H)-thione (I)
and X ray structure analysis of 3, 3'-methylenebis (4-hydroxy-1-methylquinolin-2 (1H)-one …

[引用][C] Development in the Chemotherapy of Infectious Diseases caused by Intracellular Pathogenic Protozoa: Trypanosoma and Leishmania

W Souza - Current Pharmaceutical Design, 2021 - ingentaconnect.com
The first one is Chagas disease, also known as American trypanosomiasis, caused by
Trypanosoma cruzi. This disease is found in around 6.2 million people, mainly living in Latin …