Balanced immunity is pivotal for health and homeostasis. CD4+ helper T (Th) cells are
central to the balance between immune tolerance and immune rejection. Th cells adopt …

BACKGROUND Endometriosis, a common oestrogen-dependent inflammatory disorder in
women of reproductive age, is characterized by endometrial-like tissue outside its normal …

Regulatory T (Treg) cells play a vital role in maintaining the immunosuppressive tumor
microenvironment. Lactate is a crucial metabolite in cancer and is related to tumor …

We present an integrated analysis of the clinical measurements, immune cells, and plasma
multi-omics of 139 COVID-19 patients representing all levels of disease severity, from serial …

The novel severe acute respiratory syndrome coronavirus 2, the cause of the coronavirus
disease 2019 (COVID-19) pandemic, has ravaged the world, with over 22 million total cases …

Behcet's disease (BD) is a chronic systemic inflammatory vasculitis of unknown etiology
characterized by recurrent episodes of oral aphthous ulcers, genital ulcers, skin lesions …

Long noncoding RNAs play a pivotal role in T-helper cell development but little is known
about their roles in Treg differentiation and functions during the progression of …

Natural killer (NK) cells can induce an antigen-independent immune response against
malignant cells. A growing number of scientific reports and clinical studies have shown …

Natural killer cells are important effector lymphocytes of the innate immune system, playing
critical roles in antitumor and anti-infection host defense. Tumor progression or chronic …

The importance of the microbiome to human health is increasingly recognized and has
become a major focus of recent research. However, much of the work has focused on a few …