The importance of 3D fibre architecture in cancer and implications for biomaterial model design

JC Ashworth, TR Cox - Nature Reviews Cancer, 2024 - nature.com
The need for improved prediction of clinical response is driving the development of cancer
models with enhanced physiological relevance. A new concept of 'precision biomaterials' is …

Crosstalk between T lymphocyte and extracellular matrix in tumor microenvironment

D Lv, Y Fei, H Chen, J Wang, W Han, B Cui… - Frontiers in …, 2024 - frontiersin.org
The extracellular matrix (ECM) is a complex three-dimensional structure composed of
proteins, glycans, and proteoglycans, constituting a critical component of the tumor …

Tenascin-C targeting strategies in cancer

S Dhaouadi, B Bouhaouala-Zahar, G Orend - Matrix Biology, 2024 - Elsevier
Tenascin-C (TNC) is a matricellular and multimodular glycoprotein highly expressed under
pathological conditions, especially in cancer and chronic inflammatory diseases. Since a …

Pancreatic stellate cells and the interleukin family: Linking fibrosis and immunity to pancreatic ductal adenocarcinoma

H Li, D Liu, K Li, Y Wang… - Molecular Medicine …, 2024 - spandidos-publications.com
Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive form of cancer with a
low survival rate. A successful treatment strategy should not be limited to targeting cancer …

Biomimetic Hydrogel Strategies for Cancer Therapy

AM Alshehri, OC Wilson - Gels, 2024 - mdpi.com
Recent developments in biomimetic hydrogel research have expanded the scope of
biomedical technologies that can be used to model, diagnose, and treat a wide range of …