[HTML][HTML] Transcriptome profiling in human diseases: new advances and perspectives

A Casamassimi, A Federico, M Rienzo… - International journal of …, 2017 - mdpi.com
In the last decades, transcriptome profiling has been one of the most utilized approaches to
investigate human diseases at the molecular level. Through expression studies, many …

Inflammatory bowel disease: tri-directional relationship between microbiota, immune system and intestinal epithelium

S Ahlawat, P Kumar, H Mohan, S Goyal… - Critical Reviews in …, 2021 - Taylor & Francis
Human gut microbiota contributes to host nutrition and metabolism, sustains intestinal cell
proliferation and differentiation, and modulates host immune system. The alterations in their …

[HTML][HTML] Proteomics and lipidomics in inflammatory bowel disease research: from mechanistic insights to biomarker identification

B Titz, RM Gadaleta, G Lo Sasso, A Elamin… - International journal of …, 2018 - mdpi.com
Inflammatory bowel disease (IBD) represents a group of progressive disorders characterized
by recurrent chronic inflammation of the gut. Ulcerative colitis and Crohn′ s disease are the …

[HTML][HTML] Mucosal metabolomic profiling and pathway analysis reveal the metabolic signature of ulcerative colitis

J Diab, T Hansen, R Goll, H Stenlund, E Jensen… - Metabolites, 2019 - mdpi.com
The onset of ulcerative colitis (UC) is characterized by a dysregulated mucosal immune
response triggered by several genetic and environmental factors in the context of host …

Integrative analysis of transcriptomic and proteomic profiling in inflammatory bowel disease colon biopsies

L Jin, L Li, C Hu, J Paez-Cortez, Y Bi… - Inflammatory bowel …, 2019 - academic.oup.com
Background Crohn's disease (CD) and ulcerative colitis (UC) are intestinal chronic
inflammatory conditions characterized by altered epithelial barrier function and tissue …

Surface-enhanced Raman scattering for the diagnosis of ulcerative colitis: will it change the rules of the game?

C Tefas, R Mărginean, V Toma, B Petrushev… - Analytical and …, 2021 - Springer
Ulcerative colitis (UC) is a relapsing-remitting inflammatory bowel disease that requires
numerous costly invasive investigations which lead to physical and psychological patient …

[HTML][HTML] A systems biology analysis protein-protein interaction of NASH and IBD based on comprehensive gene information

R Karbalaei, M Piran, M Rezaei-Tavirani… - … and hepatology from …, 2017 - ncbi.nlm.nih.gov
Aim: Analysis reconstruction networks from two diseases, IBD and NASH and their
relationship, based on systems biology methods. Background: IBD and NASH are two …

High-dimensionality data analysis of pharmacological systems associated with complex diseases

JO Hendrickx, J van Gastel, H Leysen, B Martin… - Pharmacological …, 2020 - ASPET
It is widely accepted that molecular reductionist views of highly complex human physiologic
activity, eg, the aging process, as well as therapeutic drug efficacy are largely …

Multiomics-based strategies for taming intestinal inflammation in the neonate

J Neu - Current Opinion in Clinical Nutrition & Metabolic Care, 2019 - journals.lww.com
Multiomics-based strategies for taming intestinal inflammati... : Current Opinion in Clinical
Nutrition & Metabolic Care Multiomics-based strategies for taming intestinal inflammation in the …

[HTML][HTML] Systems biology in inflammatory bowel diseases: on the way to precision medicine

N Dovrolis, E Filidou, G Kolios - Annals of Gastroenterology, 2019 - ncbi.nlm.nih.gov
Inflammatory bowel diseases (IBD) are chronic and recurrent inflammatory disorders of the
gastrointestinal tract. The elucidation of their etiopathology requires complex and multiple …