Dapansutrile OLT1177 Suppresses Foreign Body Response Inflammation while Preserving Vascularisation of Implanted Materials

AHP Chan, X Xu, I Chin, A Grant, K Lau, Y Hu… - Journal of Materials …, 2024 - pubs.rsc.org
Mitigating inflammation associated with the foreign body response (FBR) remains a
significant challenge in enhancing the performance of implantable medical devices. Current …

[HTML][HTML] MCC950 attenuates plasma cell mastitis in an MDSC-dependent manner

X Sun, J Hou, T Ni, Z Xu, W Yan, L Kong… - International …, 2024 - Elsevier
Plasma cell mastitis (PCM) is a sterile inflammatory condition primarily characterized by
periductal inflammation and ductal ectasia. Currently, there is a lack of non-invasive or …

Modulation of the Immune System to Improve Tissue Regeneration Strategies

LG Bracaglia, TR Kyriakides - Tissue Engineering Part A, 2024 - liebertpub.com
Awide range of implanted biomaterials, tissue en-gineered scaffolds, and devices interact
with the immune system via complex and not well-understood mechanisms. This is due, in …