Alterations of Vaginal Microbiota and Chlamydia trachomatis as Crucial Co-Causative Factors in Cervical Cancer Genesis Procured by HPV

C Gargiulo Isacco, MG Balzanelli, S Garzone… - Microorganisms, 2023 - mdpi.com
Chlamydia trachomatis and human papillomavirus (HPV) are the most common pathogens
found in sexually transmitted infections (STIs), and both are known to increase the risk of …

Commonalities and Disparities between Endometriosis and Chronic Endometritis: Therapeutic Potential of Novel Antibiotic Treatment Strategy against Ectopic …

K Kitaya, T Yasuo - International Journal of Molecular Sciences, 2023 - mdpi.com
Chronic endometritis (CE) is a local mucosal inflammatory disorder of the uterine lining,
which is histopathologically recognized as the unusual infiltration of CD138 (+) plasmacytes …

Crosstalk between the resident microbiota and the immune cells regulates female genital tract health

L Santacroce, R Palmirotta, L Bottalico, IA Charitos… - Life, 2023 - mdpi.com
The female genital tract (FGT) performs several functions related to reproduction, but due to
its direct exposure to the external environment, it may suffer microbial infections. Both the …

Predictive biomarkers for anti-TNF alpha therapy in IBD patients

M Kumar, S Murugesan, N Ibrahim, M Elawad… - Journal of Translational …, 2024 - Springer
Inflammatory bowel disease (IBD) is a chronic gastrointestinal condition characterized by
severe gut inflammation, commonly presenting as Crohn's disease, ulcerative colitis or …

A Narrative Review Discussing the Obstetric Repercussions Due to Alterations of Personalized Bacterial Sites Developed within the Vagina, Cervix, and Endometrium

B Doroftei, OD Ilie, T Armeanu, IL Stoian… - Journal of Clinical …, 2023 - mdpi.com
Background: The reproductive tract microbiota that evolved as an integrative component has
been studied intensively in the last decade. As a result, novel research, clinical …

Metagenomic analysis reveals a dynamic microbiome with diversified adaptive functions that respond to ovulation regulation in the mouse endometrium

S Pu, M Wang, J Wang, Q Zhang, X Ma, R Wang, S Yu… - BMC genomics, 2023 - Springer
Understanding the microflora inhabiting the reproductive tract is important for a better
understanding of female physiology and reproductive health. The endometrial fluid from …

The role of microbiota in the management of genitourinary syndrome of menopause

G Stabile, GA Topouzova, F De Seta - Climacteric, 2023 - Taylor & Francis
It is estimated that the 25–50% of women who are reaching menopause every year report
symptoms related to the genitourinary syndrome of menopause (GSM). The symptoms are …

Novel delivery systems for controlled release of bacterial therapeutics

N Zaragoza, GI Anderson, S Allison-Logan… - Trends in …, 2024 - cell.com
As more is learned about the benefits of microbes, their potential to prevent and treat
disease is expanding. Microbial therapeutics are less burdensome and costly to produce …

Deciphering the role of female reproductive tract microbiome in reproductive health: a review

H Gao, Q Liu, X Wang, T Li, H Li, G Li, L Tan… - Frontiers in Cellular …, 2024 - frontiersin.org
Relevant studies increasingly indicate that female reproductive health is confronted with
substantial challenges. Emerging research has revealed that the microbiome interacts with …

Optimal sampling and analysis methods for clinical diagnostics of vaginal microbiome

K Kero, N Hieta, T Kallonen, A Ahtikoski… - European Journal of …, 2023 - Springer
Next-generation sequencing-based microbiological analysis is a complex way to profile
vaginal microbiome samples since each step affects the results gained. Methodologies for …