Toward neurosubtypes in autism

SJ Hong, JT Vogelstein, A Gozzi, BC Bernhardt… - Biological …, 2020 - Elsevier
There is a consensus that substantial heterogeneity underlies the neurobiology of autism
spectrum disorder (ASD). As such, it has become increasingly clear that a dissection of …

From pattern classification to stratification: towards conceptualizing the heterogeneity of Autism Spectrum Disorder

T Wolfers, DL Floris, R Dinga, D van Rooij… - Neuroscience & …, 2019 - Elsevier
Pattern classification and stratification approaches have increasingly been used in research
on Autism Spectrum Disorder (ASD) over the last ten years with the goal of translation …

[HTML][HTML] Shared and unique brain network features predict cognitive, personality, and mental health scores in the ABCD study

J Chen, A Tam, V Kebets, C Orban, LQR Ooi… - Nature …, 2022 - nature.com
How individual differences in brain network organization track behavioral variability is a
fundamental question in systems neuroscience. Recent work suggests that resting-state and …

[HTML][HTML] One size does not fit all: methodological considerations for brain-based predictive modeling in psychiatry

E Dhamala, BTT Yeo, AJ Holmes - Biological Psychiatry, 2023 - Elsevier
Psychiatric illnesses are heterogeneous in nature. No illness manifests in the same way
across individuals, and no two patients with a shared diagnosis exhibit identical symptom …

[HTML][HTML] Atypical brain asymmetry in autism—a candidate for clinically meaningful stratification

DL Floris, T Wolfers, M Zabihi, NE Holz… - Biological Psychiatry …, 2021 - Elsevier
Background Autism spectrum disorder (“autism”) is a highly heterogeneous
neurodevelopmental condition with few effective treatments for core and associated …

Decomposing MRI phenotypic heterogeneity in epilepsy: a step towards personalized classification

HM Lee, F Fadaie, R Gill, B Caldairou, V Sziklas… - Brain, 2022 - academic.oup.com
In drug-resistant temporal lobe epilepsy, precise predictions of drug response, surgical
outcome and cognitive dysfunction at an individual level remain challenging. A possible …

A new approach to diagnosing and researching developmental prosopagnosia: Excluded cases are impaired too

EJ Burns, E Gaunt, B Kidane, L Hunter… - Behavior research …, 2023 - Springer
Developmental prosopagnosia is characterized by severe, lifelong difficulties when
recognizing facial identity. Unfortunately, the most common diagnostic assessment …

Fractionating autism based on neuroanatomical normative modeling

M Zabihi, DL Floris, SM Kia, T Wolfers… - Translational …, 2020 - nature.com
Autism is a complex neurodevelopmental condition with substantial phenotypic, biological,
and etiologic heterogeneity. It remains a challenge to identify biomarkers to stratify autism …

Mapping the heterogeneous brain structural phenotype of autism spectrum disorder using the normative model

X Shan, LQ Uddin, J Xiao, C He, Z Ling, L Li… - Biological …, 2022 - Elsevier
Background Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder
characterized by substantial clinical and biological heterogeneity. Quantitative and …

Structural, functional, and molecular imaging of autism spectrum disorder

X Li, K Zhang, X He, J Zhou, C Jin, L Shen, Y Gao… - Neuroscience …, 2021 - Springer
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder
associated with both genetic and environmental risks. Neuroimaging approaches have been …