As a metabolic organ, adipose tissue plays an important role in regulating metabolism. In
adults, most adipose tissue is white adipose tissue (WAT), and excessive expansion of WAT …

Obesity is a major public health problem and is related to increasing rates of cardiovascular
morbidity and mortality. Over 1.9 billion adults are overweight or obese worldwide and the …

Aims The major pathological mechanisms of osteoarthritis (OA) progression include
inflammation, autophagy, and apoptosis, etc. Moderate mechanical strain and exercise …

Increasing evidence shows that endothelial cells play critical roles in maintaining vascular
homeostasis, regulating vascular tone, inhibiting inflammatory response, suppressing lipid …

Background Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common
liver disease. Exercise is an effective strategy against NAFLD, but its underlying molecular …

Acute and chronic animal models of exercise are commonly used in research. Acute
exercise testing is used, often in combination with genetic, pharmacological, or other …

Abstract Cysteine dioxygenase type 1 (CDO1), belonging to the mammalian non-heme Fe
(II) dioxygenases family, is a key enzyme for cysteine catabolism. Its activity and expression …

Objective Due to the increasing prevalence of obesity and insulin resistance, there is an
urgent need for better treatment of obesity and its related metabolic disorders. This study …

Traumatic brain injury (TBI), also known as a silent epidemic, is currently a substantial public
health problem worldwide. Given the increased energy demands following brain injury …

Aims To investigate whether transient dietary restriction or aerobic exercise in young
adulthood exert long-lasting protection against brain aging later in life. Main methods Seven …