[HTML][HTML] Functional classification and experimental dissection of long noncoding RNAs
F Kopp, JT Mendell - Cell, 2018 - cell.com
Over the last decade, it has been increasingly demonstrated that the genomes of many
species are pervasively transcribed, resulting in the production of numerous long noncoding …
species are pervasively transcribed, resulting in the production of numerous long noncoding …
Long noncoding RNAs as biomarkers in cancer
L Bolha, M Ravnik-Glavač, D Glavač - Disease markers, 2017 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are a relatively well‐characterized class of noncoding
RNA (ncRNA) molecules, involved in the regulation of various cell processes, including …
RNA (ncRNA) molecules, involved in the regulation of various cell processes, including …
Long noncoding RNA MALAT1 regulates endothelial cell function and vessel growth
KM Michalik, X You, Y Manavski… - Circulation …, 2014 - Am Heart Assoc
Rationale: The human genome harbors a large number of sequences encoding for RNAs
that are not translated but control cellular functions by distinct mechanisms. The expression …
that are not translated but control cellular functions by distinct mechanisms. The expression …
Immunobiology of long noncoding RNAs
MK Atianand, DR Caffrey… - Annual review of …, 2017 - annualreviews.org
The discovery of long noncoding RNAs (lncRNA) has provided a new perspective on gene
regulation in diverse biological contexts. lncRNAs are remarkably versatile molecules that …
regulation in diverse biological contexts. lncRNAs are remarkably versatile molecules that …
[HTML][HTML] Long noncoding RNAs in cancer: mechanisms of action and technological advancements
The previous decade has seen long non-coding RNAs (lncRNAs) rise from obscurity to
being defined as a category of genetic elements, leaving its mark on the field of cancer …
being defined as a category of genetic elements, leaving its mark on the field of cancer …
[HTML][HTML] Braveheart, a long noncoding RNA required for cardiovascular lineage commitment
CA Klattenhoff, JC Scheuermann, LE Surface… - Cell, 2013 - cell.com
Long noncoding RNAs (lncRNAs) are often expressed in a development-specific manner,
yet little is known about their roles in lineage commitment. Here, we identified Braveheart …
yet little is known about their roles in lineage commitment. Here, we identified Braveheart …
HLA-G: an immune checkpoint molecule
ED Carosella, N Rouas-Freiss, D Tronik-Le Roux… - Advances in …, 2015 - Elsevier
HLA-G is a molecule that was first known to confer protection to the fetus from destruction by
the immune system of its mother, thus critically contributing to fetal–maternal tolerance. The …
the immune system of its mother, thus critically contributing to fetal–maternal tolerance. The …
Long noncoding RNAs and microRNAs in cardiovascular pathophysiology
T Thum, G Condorelli - Circulation research, 2015 - Am Heart Assoc
RNAs not encoding proteins have gained prominence over the last couple of decades as
fundamental regulators of cellular function. Not surprisingly, their dysregulation is …
fundamental regulators of cellular function. Not surprisingly, their dysregulation is …
Long noncoding RNAs regulate adipogenesis
The prevalence of obesity has led to a surge of interest in understanding the detailed
mechanisms underlying adipocyte development. Many protein-coding genes, mRNAs, and …
mechanisms underlying adipocyte development. Many protein-coding genes, mRNAs, and …
The Mediator complex and transcription regulation
ZC Poss, CC Ebmeier, DJ Taatjes - Critical reviews in biochemistry …, 2013 - Taylor & Francis
The Mediator complex is a multi-subunit assembly that appears to be required for regulating
expression of most RNA polymerase II (pol II) transcripts, which include protein-coding and …
expression of most RNA polymerase II (pol II) transcripts, which include protein-coding and …