Many people in the world struggle with cancer or bacterial, parasitic, viral, Alzheimer's and
other diseases. Therefore, many scientists seek new, more effective, more selective and less …

'Acridine'along with its functional analogue 'Acridone'is the most privileged pharmacophore
in medicinal chemistry with diverse applications ranging from DNA intercalators …

Catalytic dehydrogenation (CDH) is one of the most important reactions in the manufacturing
of commodity chemicals.[1] For instance, annually approximately 17 million tons of styrene …

We report formal [3+ 3] annulations of aromatic azides with aromatic imines and
azobenzenes to give acridines and phenazines, respectively. These transformations …

Malaria has been a human health concern ever since the dawn of mankind, but despite the
huge struggles made to date to fight this infection, in 2012 over half a million people were …

The development of drug resistance and severe side-effects has reduced the clinical efficacy
of the existing anti-cancer drugs available in the market. Thus, there is always a constant …

Introduction: Acridine derivatives have been extensively explored as potential therapeutic
agents for the treatment of a number of diseases, such as cancer, Alzheimer's, and bacterial …

A number of acridone-based oxadiazoles 11a–n have been synthesized and evaluated for
their anticonvulsant activity against pentylenetetrazole (PTZ)-and maximal electroshock …

The click chemistry is one of the most powerful C− N bond forming‐reactions towards five‐
membered heterocycles. The copper‐catalyzed azide‐alkyne cycloaddition (CuAAC) has …

The discovery of new effective DNA-targeted antitumor agent is needed because of their
clinical significance. As acridines can intercalate into DNA and benzimidazoles have the …