NF螃B as a regulator of cancer metastasis and therapy response: A focus on epithelial–mesenchymal transition

S Mirzaei, S Saghari, F Bassiri, R Raesi… - Journal of cellular …, 2022 - Wiley Online Library
Metastasis of tumor cells is a complex challenge and significantly diminishes the overall
survival and prognosis of cancer patients. The epithelialtomesenchymal transition (EMT) …

Chitosanbased nanoscale systems for doxorubicin delivery: Exploring biomedical application in cancer therapy

M Ashrafizadeh, K Hushmandi… - Bioengineering & …, 2023 - Wiley Online Library
Green chemistry has been a growing multidisciplinary field in recent years showing great
promise in biomedical applications, especially for cancer therapy. Chitosan (CS) is an …

[HTML][HTML] Pre-clinical and clinical importance of miR-21 in human cancers: Tumorigenesis, therapy response, delivery approaches and targeting agents

M Hashemi, MSA Mirdamadi, Y Talebi… - Pharmacological …, 2023 - Elsevier
The field of non-coding RNA (ncRNA) has made significant progress in understanding the
pathogenesis of diseases and has broadened our knowledge towards their targeting …

[HTML][HTML] Targeted regulation of autophagy using nanoparticles: New insight into cancer therapy

MDA Paskeh, M Entezari, C Clark, A Zabolian… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Normal cells depend on autophagy to maintain cellular homeostasis by recycling damaged
organelles and misfolded proteins and degrading toxic agents. Similar to apoptosis …

Long non-coding RNA/epithelial-mesenchymal transition axis in human cancers: Tumorigenesis, chemoresistance, and radioresistance

M Hashemi, S Hajimazdarany, CD Mohan… - Pharmacological …, 2022 - Elsevier
Epithelial-to-mesenchymal transition (EMT) is a process that involves the transformation of
polarized epithelial cells to attain a mesenchymal phenotype that presents an elevated …

Nanoliposomes for doxorubicin delivery: Reversing drug resistance, stimuli-responsive carriers and clinical translation

M Hashemi, F Ghadyani, S Hasani, Y Olyaee… - Journal of Drug Delivery …, 2023 - Elsevier
Cancer is still a major threat to human life that is characterized by abnormal proliferation and
metastasis of cancer cells. Chemotherapy is procedure of using anti-cancer drugs for …

Deciphering STAT3 signaling potential in hepatocellular carcinoma: tumorigenesis, treatment resistance, and pharmacological significance

M Hashemi, E Sabouni, P Rahmanian… - Cellular & molecular …, 2023 - Springer
Hepatocellular carcinoma (HCC) is considered one of the greatest challenges to human life
and is the most common form of liver cancer. Treatment of HCC depends on chemotherapy …

Gold nanostructure-mediated delivery of anticancer agents: Biomedical applications, reversing drug resistance, and stimuli-responsive nanocarriers

M Entezari, GGY Abad, B Sedghi, R Ettehadi… - Environmental …, 2023 - Elsevier
The application of nanoarchitectures in cancer therapy seems to be beneficial for the
delivery of antitumor drugs. In recent years, attempts have been made to reverse drug …

Targeting cancer stem cells by dietary agents: an important therapeutic strategy against human malignancies

M Deldar Abad Paskeh, S Asadi, A Zabolian… - International Journal of …, 2021 - mdpi.com
As a multifactorial disease, treatment of cancer depends on understanding unique
mechanisms involved in its progression. The cancer stem cells (CSCs) are responsible for …

Pre-clinical and clinical applications of small interfering RNAs (siRNA) and co-delivery systems for pancreatic cancer therapy

S Mirzaei, MH Gholami, HL Ang, F Hashemi, A Zarrabi… - Cells, 2021 - mdpi.com
Pancreatic cancer (PC) is one of the leading causes of death and is the fourth most
malignant tumor in men. The epigenetic and genetic alterations appear to be responsible for …