[HTML][HTML] Host-parasite interactions during Plasmodium infection: Implications for immunotherapies
Malaria is a global infectious disease that remains a leading cause of morbidity and mortality
in the developing world. Multiple environmental and host and parasite factors govern the …
in the developing world. Multiple environmental and host and parasite factors govern the …
[HTML][HTML] Trends of malaria infection in pregnancy in Ghana over the past two decades: a review
Background There has been a global decline in malaria transmission over the past decade.
However, not much is known of the impact of this observation on the burden of malaria …
However, not much is known of the impact of this observation on the burden of malaria …
[HTML][HTML] Structure-guided design of VAR2CSA-based immunogens and a cocktail strategy for a placental malaria vaccine
R Ma, ND Salinas, S Orr-Gonzalez… - PLoS …, 2024 - journals.plos.org
Placental accumulation of Plasmodium falciparum infected erythrocytes results in maternal
anemia, low birth weight, and pregnancy loss. The parasite protein VAR2CSA facilitates the …
anemia, low birth weight, and pregnancy loss. The parasite protein VAR2CSA facilitates the …
A single full-length VAR2CSA ectodomain variant purifies broadly neutralizing antibodies against placental malaria isolates
JYA Doritchamou, JP Renn, B Jenkins, A Mahamar… - Elife, 2022 - elifesciences.org
Placental malaria (PM) is a deadly syndrome most frequent and severe in first pregnancies.
PM results from accumulation of Plasmodium falciparum-infected erythrocytes (IE) that …
PM results from accumulation of Plasmodium falciparum-infected erythrocytes (IE) that …
[HTML][HTML] The Need for Novel Asexual Blood-Stage Malaria Vaccine Candidates for Plasmodium falciparum
E Takashima, H Otsuki, M Morita, D Ito, H Nagaoka… - Biomolecules, 2024 - mdpi.com
Extensive control efforts have significantly reduced malaria cases and deaths over the past
two decades, but in recent years, coupled with the COVID-19 pandemic, success has …
two decades, but in recent years, coupled with the COVID-19 pandemic, success has …
Protective efficacy and correlates of immunity of immunodominant recombinant Babesia microti antigens
S Meredith, V Majam, H Zheng, N Verma… - Infection and …, 2023 - Am Soc Microbiol
Babesia microti, an intraerythrocytic apicomplexan parasite, is the primary causative agent
of human babesiosis and an emerging threat to public health in the United States and …
of human babesiosis and an emerging threat to public health in the United States and …
[HTML][HTML] Recent advances on vaccines against malaria: A review
S Malik, Y Waheed - Asian Pacific Journal of Tropical Medicine, 2024 - journals.lww.com
This review aims to summarize the currently viable vaccine strategies including the
approved vaccines and the those in trials for next-generation malaria vaccines. Data on …
approved vaccines and the those in trials for next-generation malaria vaccines. Data on …
[HTML][HTML] Malaria in pregnancy: adverse pregnancy outcomes and the future of prevention
AD Berhe, JYA Doritchamou, PE Duffy - Frontiers in Tropical …, 2023 - frontiersin.org
Malaria in pregnancy (MiP) poses a dangerous health risk to both mothers and their fetuses,
causing severe outcomes such as preterm delivery, intrauterine growth restriction …
causing severe outcomes such as preterm delivery, intrauterine growth restriction …
[HTML][HTML] Polymorphic Molecular Signatures in Variable Regions of the Plasmodium falciparum var2csa DBL3x Domain Are Associated with Virulence in Placental …
The Plasmodium falciparum protein VAR2CSA allows infected erythrocytes to accumulate
within the placenta, inducing pathology and poor birth outcomes. Multiple exposures to …
within the placenta, inducing pathology and poor birth outcomes. Multiple exposures to …
[HTML][HTML] Biological strategies and political hurdles in developing malaria vaccines
MF Good, DI Stanisic - Expert Review of Vaccines, 2021 - Taylor & Francis
Malaria is a devastating parasitic disease for which a vaccine is urgently needed. Seminal
studies in the 1940s demonstrated that a whole parasite malaria vaccine could induce …
studies in the 1940s demonstrated that a whole parasite malaria vaccine could induce …