Mechanisms of apoptosis modulation by curcumin: Implications for cancer therapy

K Mortezaee, E Salehi… - Journal of cellular …, 2019 - Wiley Online Library
Cancer incidences are growing and cause millions of deaths worldwide. Cancer therapy is
one of the most important challenges in medicine. Improving therapeutic outcomes from …

Modern radiotherapy concepts and the impact of radiation on immune activation

L Deloch, A Derer, J Hartmann, B Frey, R Fietkau… - Frontiers in …, 2016 - frontiersin.org
Even though there is extensive research carried out in radiation oncology, most of the
clinical studies focus on the effects of radiation on the local tumor tissue and deal with …

A review on curability of cancers: more efforts for novel therapeutic options are needed

S Wang, Y Liu, Y Feng, J Zhang, J Swinnen, Y Li, Y Ni - Cancers, 2019 - mdpi.com
Cancer remains a major cause of death globally. Given its relapsing and fatal features,
curing cancer seems to be something hardly possible for the majority of patients. In view of …

A prospective strategy leveraging nanomedicine for cancer therapy: pouring ferroptosis on apoptosis

Y Xia, J Zhang, G Liu - Nano Today, 2023 - Elsevier
As a fundamental process of the programmed cell death, apoptosis has endowed
nanomedicine broad horizons to treat tumor. However, apoptosis-resistance elicited by …

Chromatin and the cellular response to particle radiation-induced oxidative and clustered DNA damage

JM Danforth, L Provencher… - Frontiers in Cell and …, 2022 - frontiersin.org
Exposure to environmental ionizing radiation is prevalent, with greatest lifetime doses
typically from high Linear Energy Transfer (high-LET) alpha particles via the radioactive …

The molecular basis of targeting protein kinases in cancer therapeutics

CJ Tsai, R Nussinov - Seminars in cancer biology, 2013 - Elsevier
In this paper, we provide an overview of targeted anticancer therapies with small molecule
kinase inhibitors. First, we discuss why a single constitutively active kinase emanating from a …

Carbonic anhydrase IX (CAIX), cancer, and radiation responsiveness

C Ward, J Meehan, M Gray, IH Kunkler, SP Langdon… - Metabolites, 2018 - mdpi.com
Carbonic anhydrase IX has been under intensive investigation as a therapeutic target in
cancer. Studies demonstrate that this enzyme has a key role in pH regulation in cancer cells …

Multifunctional Bi2S3/PLGA nanocapsule for combined HIFU/radiation therapy

M Yao, M Ma, Y Chen, X Jia, G Xu, H Xu, H Chen… - Biomaterials, 2014 - Elsevier
A multifunctional organic-inorganic hybrid nanocapsule based on Bi 2 S 3-embedded poly
(lactic-co-glycolic acid)(PLGA) nanocapsule has been elaborately designed to combine the …

Near-infrared photoimmunotherapy (NIR-PIT) in urologic cancers

H Fukushima, B Turkbey, PA Pinto, A Furusawa… - Cancers, 2022 - mdpi.com
Simple Summary Near-infrared photoimmunotherapy (NIR-PIT) is a novel molecularly-
targeted therapy that induces rapid cancer cell death by systemically administering an …

The future of radiation-induced abscopal response: beyond conventional radiotherapy approaches

S Tubin, W Yan, WF Mourad, P Fossati… - Future Oncology, 2020 - Taylor & Francis
Advances in the immunological pharmaceuticals, such as checkpoint inhibitors and
agonists, have positive implications for the future of the radiotherapy abscopal response. A …