Vision impairment and loss due to posterior segment ocular disorders, including age-related
macular degeneration and diabetic retinopathy, are a rapidly growing cause of disability …

The validation of prostate specific membrane antigen (PSMA) as a molecular target in
metastatic castration-resistant prostate cancer has stimulated the development of multiple …

Neurodegenerative diseases are a major global health burden particularly with the
increasing ageing population. Hereditary predisposition and environmental risk factors …

Dendrimers are polymers with well‐defined 3D branched structures that are vastly utilized in
various neurotheranostics and biomedical applications, particularly as nanocarrier vectors …

Glutamate carboxypeptidase-II (GCPII) expression in brain is increased by inflammation, eg
by COVID19 infection, where it reduces NAAG stimulation of metabotropic glutamate …

Neuroinflammatory disorders preferentially impair the higher cognitive and executive
functions of the prefrontal cortex (PFC). This includes such challenging disorders as …

Neurodegenerative diseases (NDs), such as Parkinson's Disease (PD), Alzheimer's Disease
(AD), Multiple Sclerosis (MS) and amyotrophic lateral sclerosis (ALS), are characterized by …

The blood–brain barrier (BBB) is a tailored system of capillary endothelial cells intermixed
with tight junctions and adherent junctions that regulates the transport of various materials …

Sustained cognitive deficits are a common and debilitating feature of “long COVID”, but
currently there are no FDA-approved treatments. The cognitive functions of the dorsolateral …

Abstract Background Cognitive decline in Alzheimer's disease (AD) is associated with
hyperphosphorylated tau (pTau) propagation between neurons along synaptically …