The efficacy and safety of JAK inhibitors for alopecia areata: a systematic review and meta-analysis of prospective studies

D Yan, H Fan, M Chen, L Xia, S Wang… - Frontiers in …, 2022 - frontiersin.org
Background: Due to the lack of comprehensive evidence based on prospective studies, the
efficacy and safety of Janus Kinase (JAK) inhibitors (including tofacitinib, ruxolitinib …

[HTML][HTML] Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature

Y Shimizu, EH Ntege, H Sunami, Y Inoue - Regenerative therapy, 2022 - Elsevier
Hair loss, or alopecia, is associated with several psychosocial and medical comorbidities,
and it remains an economic burden to individuals and the society. Alopecia is attributable to …

Two phase 3 trials of baricitinib for alopecia areata

B King, M Ohyama, O Kwon, A Zlotogorski… - … England Journal of …, 2022 - Mass Medical Soc
Background Alopecia areata is an autoimmune condition characterized by rapid hair loss in
the scalp, eyebrows, and eyelashes, for which treatments are limited. Baricitinib, an oral …

Phase 2a randomized clinical trial of dupilumab (anti‐IL‐4Rα) for alopecia areata patients

E Guttman‐Yassky, Y Renert‐Yuval, J Bares… - Allergy, 2022 - Wiley Online Library
Background Treatments for alopecia areata (AA) patients with extensive scalp hair loss are
limited, and recent evidence supports a role for type 2 T‐cell (Th2)‐immune response in AA …

Alopecia areata–Current understanding and management

DA Lintzeri, A Constantinou, K Hillmann… - JDDG: Journal der …, 2022 - Wiley Online Library
Alopecia areata (AA) is a chronic, immune‐mediated disease characterized by acute or
chronic non‐scarring hair loss, with a heterogeneity in clinical manifestations ranging from …

The role of serum Th1, Th2, and Th17 cytokines in patients with alopecia areata: clinical implications

A Waśkiel-Burnat, M Osińska, A Salińska, L Blicharz… - Cells, 2021 - mdpi.com
Alopecia areata is a type of non-scarring hair loss. The dysregulation of numerous systemic
Th1 (IL-2, IFN-γ, TNF, IL-12, and IL-18), Th2 (IL-4, IL-5, IL-6, IL-9, IL-10, IL-13, IL-17E, IL-31 …

Alopecia areata: current treatments and new directions

D Dahabreh, S Jung, Y Renert-Yuval, J Bar… - American Journal of …, 2023 - Springer
Alopecia areata is an autoimmune hair loss disease that is non-scarring and is
characterized by chronic inflammation at the hair follicle level. Clinically, patients' …

Defining severity in alopecia areata: current perspectives and a multidimensional framework

BA King, MM Senna, M Ohyama, A Tosti… - Dermatology and …, 2022 - Springer
Alopecia areata (AA) is an autoimmune disease characterized by nonscarring hair loss. As a
clinically heterogeneous disease, various classification systems have evolved for defining its …

Alopecia areata treatment patterns, healthcare resource utilization, and comorbidities in the US population using insurance claims

M Senna, J Ko, A Tosti, E Edson-Heredia… - Advances in …, 2021 - Springer
Introduction Alopecia areata (AA) is an autoimmune disorder causing sudden, non-scarring
hair loss. There are currently no drugs approved for AA treatment. This study assessed …

Occurrence of inflammatory bowel disease in patients with chronic inflammatory skin diseases: a cohort study

MC Schneeweiss, J Kirchgesner, R Wyss… - British Journal of …, 2022 - academic.oup.com
Background Several studies have linked various chronic inflammatory skin diseases
(CISDs) with inflammatory bowel disease (IBD) in a range of data sources with mixed …