The efficacy and safety of JAK inhibitors for alopecia areata: a systematic review and meta-analysis of prospective studies
D Yan, H Fan, M Chen, L Xia, S Wang… - Frontiers in …, 2022 - frontiersin.org
Background: Due to the lack of comprehensive evidence based on prospective studies, the
efficacy and safety of Janus Kinase (JAK) inhibitors (including tofacitinib, ruxolitinib …
efficacy and safety of Janus Kinase (JAK) inhibitors (including tofacitinib, ruxolitinib …
[HTML][HTML] Regenerative medicine strategies for hair growth and regeneration: A narrative review of literature
Hair loss, or alopecia, is associated with several psychosocial and medical comorbidities,
and it remains an economic burden to individuals and the society. Alopecia is attributable to …
and it remains an economic burden to individuals and the society. Alopecia is attributable to …
Two phase 3 trials of baricitinib for alopecia areata
Background Alopecia areata is an autoimmune condition characterized by rapid hair loss in
the scalp, eyebrows, and eyelashes, for which treatments are limited. Baricitinib, an oral …
the scalp, eyebrows, and eyelashes, for which treatments are limited. Baricitinib, an oral …
Phase 2a randomized clinical trial of dupilumab (anti‐IL‐4Rα) for alopecia areata patients
E Guttman‐Yassky, Y Renert‐Yuval, J Bares… - Allergy, 2022 - Wiley Online Library
Background Treatments for alopecia areata (AA) patients with extensive scalp hair loss are
limited, and recent evidence supports a role for type 2 T‐cell (Th2)‐immune response in AA …
limited, and recent evidence supports a role for type 2 T‐cell (Th2)‐immune response in AA …
Alopecia areata–Current understanding and management
DA Lintzeri, A Constantinou, K Hillmann… - JDDG: Journal der …, 2022 - Wiley Online Library
Alopecia areata (AA) is a chronic, immune‐mediated disease characterized by acute or
chronic non‐scarring hair loss, with a heterogeneity in clinical manifestations ranging from …
chronic non‐scarring hair loss, with a heterogeneity in clinical manifestations ranging from …
The role of serum Th1, Th2, and Th17 cytokines in patients with alopecia areata: clinical implications
A Waśkiel-Burnat, M Osińska, A Salińska, L Blicharz… - Cells, 2021 - mdpi.com
Alopecia areata is a type of non-scarring hair loss. The dysregulation of numerous systemic
Th1 (IL-2, IFN-γ, TNF, IL-12, and IL-18), Th2 (IL-4, IL-5, IL-6, IL-9, IL-10, IL-13, IL-17E, IL-31 …
Th1 (IL-2, IFN-γ, TNF, IL-12, and IL-18), Th2 (IL-4, IL-5, IL-6, IL-9, IL-10, IL-13, IL-17E, IL-31 …
Alopecia areata: current treatments and new directions
Alopecia areata is an autoimmune hair loss disease that is non-scarring and is
characterized by chronic inflammation at the hair follicle level. Clinically, patients' …
characterized by chronic inflammation at the hair follicle level. Clinically, patients' …
Defining severity in alopecia areata: current perspectives and a multidimensional framework
Alopecia areata (AA) is an autoimmune disease characterized by nonscarring hair loss. As a
clinically heterogeneous disease, various classification systems have evolved for defining its …
clinically heterogeneous disease, various classification systems have evolved for defining its …
Alopecia areata treatment patterns, healthcare resource utilization, and comorbidities in the US population using insurance claims
Introduction Alopecia areata (AA) is an autoimmune disorder causing sudden, non-scarring
hair loss. There are currently no drugs approved for AA treatment. This study assessed …
hair loss. There are currently no drugs approved for AA treatment. This study assessed …
Occurrence of inflammatory bowel disease in patients with chronic inflammatory skin diseases: a cohort study
MC Schneeweiss, J Kirchgesner, R Wyss… - British Journal of …, 2022 - academic.oup.com
Background Several studies have linked various chronic inflammatory skin diseases
(CISDs) with inflammatory bowel disease (IBD) in a range of data sources with mixed …
(CISDs) with inflammatory bowel disease (IBD) in a range of data sources with mixed …