miRNAs role in glioblastoma pathogenesis and targeted therapy: Signaling pathways interplay

SS Elshaer, AI Abulsoud, D Fathi… - … -Research and Practice, 2023 - Elsevier
High mortality and morbidity rates and variable clinical behavior are hallmarks of
glioblastoma (GBM), the most common and aggressive primary malignant brain tumor …

Mechanisms of resistance and current treatment options for glioblastoma multiforme (GBM)

SSK Yalamarty, N Filipczak, X Li, MA Subhan… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma multiforme is one of the hardest-to-treat brain tumors, often
resistant to conventional treatments such as chemotherapy and radiation therapy. Despite …

Nanoparticles Mediated the Diagnosis and Therapy of Glioblastoma: Bypass or Cross the Blood–Brain Barrier

X Song, H Qian, Y Yu - Small, 2023 - Wiley Online Library
Glioblastoma is one of the most aggressive central nervous system malignancies with high
morbidity and mortality. Current clinical approaches, including surgical resection …

[HTML][HTML] Glioblastoma multiforme

T Kanderi, V Gupta - StatPearls [Internet], 2022 - ncbi.nlm.nih.gov
Glioblastoma Multiforme - StatPearls - NCBI Bookshelf US flag An official website of the United
States government Here's how you know NIH NLM Logo Access keys NCBI Homepage …

Temozolomide, simvastatin and acetylshikonin combination induces mitochondrial-dependent apoptosis in GBM cells, which is regulated by autophagy

S Hajiahmadi, S Lorzadeh, R Iranpour, S Karima… - Biology, 2023 - mdpi.com
Simple Summary Glioblastoma multiforme (GBM) is a deadly brain tumor. The current
chemotherapy strategies (including using temozolomide (TMZ)) is not very effective for GBM …

Exploring the past, present, and future of anti-angiogenic therapy in glioblastoma

AB Zhang, K Mozaffari, B Aguirre, V Li, R Kubba… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma is the most common malignant primary brain tumor. Despite
technological advancements and modern therapeutic agents used for treatment, the …

Chronotherapy in Glioblastoma: state of the art and future perspectives

M Petković, M Henis, O Heese, A Relógio - EBioMedicine, 2023 - thelancet.com
Circadian rhythms regulate various processes in the human body, including drug
metabolism. Chronotherapy optimizes treatment timing based on the circadian rhythm of the …

Comparative assessment of direct and indirect cold atmospheric plasma effects, based on helium and argon, on human glioblastoma: an in vitro and in vivo study

M Bakhtiyari-Ramezani, M Nohekhan, ME Akbari… - Scientific Reports, 2024 - nature.com
Recent research has highlighted the promising potential of cold atmospheric plasma (CAP)
in cancer therapy. However, variations in study outcomes are attributed to differences in …

Personalized treatment of glioblastoma: current state and future perspective

A Rončević, N Koruga, A Soldo Koruga, R Rončević… - Biomedicines, 2023 - mdpi.com
Glioblastoma (GBM) is the most aggressive glial tumor of the central nervous system.
Despite intense scientific efforts, patients diagnosed with GBM and treated with the current …

Advances in preclinical/clinical glioblastoma treatment: can nanoparticles be of help?

D Ruiz-Molina, X Mao, P Alfonso-Triguero, J Lorenzo… - Cancers, 2022 - mdpi.com
Simple Summary As one of the most lethal human cancers, glioblastoma treatment is a real
challenge because of several resistance mechanisms, including limited drug entry into the …