Natural and synthetic flavonoids: structure–activity relationship and chemotherapeutic potential for the treatment of leukemia
JC Menezes, B Orlikova, F Morceau… - Critical reviews in food …, 2016 - Taylor & Francis
Flavonoids and their derivatives are polyphenolic secondary metabolites with an extensive
spectrum of pharmacological activities, including antioxidants, antitumor, anti-inflammatory …
spectrum of pharmacological activities, including antioxidants, antitumor, anti-inflammatory …
Anticancer activity of tetrandrine by inducing pro-death apoptosis and autophagy in human gastric cancer cells
XY Bai, YG Liu, W Song, YY Li, DS Hou… - Journal of Pharmacy …, 2018 - academic.oup.com
Objectives To investigate the antitumour property of tetrandrine by inducing autophagy and
apoptosis in human gastric cancer cells, and to explore the potential molecular mechanisms …
apoptosis in human gastric cancer cells, and to explore the potential molecular mechanisms …
miR-181a sensitizes resistant leukaemia HL-60/Ara-C cells to Ara-C by inducing apoptosis
H Bai, Z Cao, C Deng, L Zhou, C Wang - Journal of cancer research and …, 2012 - Springer
Background Ara-C is one of the most commonly used drugs in the treatment of AML.
However, the development of drug resistance always prevented its further use. It has been …
However, the development of drug resistance always prevented its further use. It has been …
β‐Eudesmol induces JNK‐dependent apoptosis through the mitochondrial pathway in HL60 cells
Y Li, T Li, C Miao, J Li, W Xiao, E Ma - Phytotherapy Research, 2013 - Wiley Online Library
β‐eudesmol, a natural sesquiterpenol present in a variety of Chinese herbs, is known to
inhibit the proliferation of human tumor cells. However, the molecular mechanisms of the …
inhibit the proliferation of human tumor cells. However, the molecular mechanisms of the …
[HTML][HTML] Shikonin induces apoptosis in the human gastric cancer cells HGC-27 through mitochondria-mediated pathway
Y Hou, J Xu, X Liu, X Xia, N Li, X Bi - Pharmacognosy magazine, 2015 - ncbi.nlm.nih.gov
Background: Gastric cancer (GC) is one of the most frequently occurring digestive tract
cancers and fewer chemotherapeutic drugs for GC have shown promising results. In this …
cancers and fewer chemotherapeutic drugs for GC have shown promising results. In this …
NOAD, a novel nitric oxide donor, induces G2/M phase arrest and apoptosis in human hepatocellular carcinoma Bel-7402 cells
L Liu, D Wang, J Wang, H Ji, Y Zhang - Toxicology in Vitro, 2015 - Elsevier
Abstract O 2-(2, 4-dinitro-5-{[2-(12-en-28-bd-galactopyranosyl-oleanolate-3-yl)-oxy-2-
oxoethyl] amino} phenyl) 1-(N-hydroxyethylmethylamino) diazen-1-ium-1, 2-diolate (NOAD) …
oxoethyl] amino} phenyl) 1-(N-hydroxyethylmethylamino) diazen-1-ium-1, 2-diolate (NOAD) …
Lobocrassin B induces apoptosis of human lung cancer and inhibits tumor xenograft growth
MX Lin, SH Lin, YR Li, YH Chao, CH Lin, JH Su, CC Lin - Marine Drugs, 2017 - mdpi.com
Lobocrassin B, a natural cembrane-type compound isolated from the soft coral Lobophytum
crassum, has been shown to have significant biological effects, including anticancer activity …
crassum, has been shown to have significant biological effects, including anticancer activity …
[HTML][HTML] Nanoscale quantification of the biophysical characterization of combretastatin A-4-treated tumor cells using atomic force microscopy
Y Li, J Chen, Y Liu, W Zhang, W He, H Xu, L Liu, E Ma - Plos one, 2017 - journals.plos.org
As an inhibitor of microtubule assembly, combretastatin A-4 (CA-4)-induced biological
responses in tumor cells have been well known, but the corresponding changes in nano …
responses in tumor cells have been well known, but the corresponding changes in nano …