Bisindole natural products: A vital source for the development of new anticancer drugs
M Xu, R Peng, Q Min, S Hui, X Chen, G Yang… - European Journal of …, 2022 - Elsevier
Currently, the number of new cancer cases and deaths worldwide is increasing year on
year. In addition to the requirement for cancer prevention, the top priority is still to seek the …
year. In addition to the requirement for cancer prevention, the top priority is still to seek the …
The inhibitory effect of some natural bioactive compounds against SARS-CoV-2 main protease: insights from molecular docking analysis and molecular dynamic …
DA Abdelrheem, SA Ahmed… - … Science and Health …, 2020 - Taylor & Francis
This work aimed at evaluating the inhibitory effect of ten natural bioactive compounds (1–10)
as potential inhibitors of SARS-CoV-2-3CL main protease (PDB ID: 6LU7) and SARS-CoV …
as potential inhibitors of SARS-CoV-2-3CL main protease (PDB ID: 6LU7) and SARS-CoV …
Computer-aided discovery of bis-indole derivatives as multi-target drugs against cancer and bacterial infections: DFT, docking, virtual screening, and molecular …
Recently, more complex diseases of seemingly incurable pathology have demonstrated the
need for potent and multi-target drugs. Specific to many cancers and bacterial diseases …
need for potent and multi-target drugs. Specific to many cancers and bacterial diseases …
[HTML][HTML] Experimentally and theoretically approaches for disperse red 60 dye adsorption on novel quaternary nanocomposites
NK Soliman, AF Moustafa, HRA El-Mageed… - Scientific Reports, 2021 - nature.com
A comprehensive study that combined both experimental and computational experiments
was performed to evaluate the usage of organo-metal oxide nanocomposite for the …
was performed to evaluate the usage of organo-metal oxide nanocomposite for the …
Boron nitride nanoclusters, nanoparticles and nanotubes as a drug carrier for isoniazid anti-tuberculosis drug, computational chemistry approaches
HRA El-Mageed, FM Mustafa… - Journal of Biomolecular …, 2022 - Taylor & Francis
In this work, the ability of B12N12 fullerene-like nanoclusters as a drug carrier for isoniazid
anti-tuberculosis drug has been studied by DFT methods. Binding energies in both gas and …
anti-tuberculosis drug has been studied by DFT methods. Binding energies in both gas and …
[HTML][HTML] Seasonal changes in the biochemical composition of dominant macroalgal species along the Egyptian Red Sea Shore
Simple Summary Macroalgae play a significant role as primary producers in marine
ecosystems. The most dominant species at the three collection sites studied along the …
ecosystems. The most dominant species at the three collection sites studied along the …
[HTML][HTML] Combination and tricombination therapy to destabilize the structural integrity of COVID-19 by some bioactive compounds with antiviral drugs: insights from …
HRA El-Mageed, DA Abdelrheem, SA Ahmed… - Structural …, 2021 - Springer
Abstract Recently, the SARS-CoV-2 (COVID-19) pandemic virus has been spreading
throughout the world. Until now, no certified drugs have been discovered to efficiently inhibit …
throughout the world. Until now, no certified drugs have been discovered to efficiently inhibit …
[HTML][HTML] Pro-Apoptotic Activity and Cell Cycle Arrest of Caulerpa sertularioides against SKLU-1 Cancer Cell in 2D and 3D Cultures
R Agena, ADJ Cortés-Sánchez, H Hernández-Sánchez… - Molecules, 2023 - mdpi.com
Cancer is a disease with the highest mortality and morbidity rate worldwide. First-line drugs
induce several side effects that drastically reduce the quality of life of people with this …
induce several side effects that drastically reduce the quality of life of people with this …
Molecular Networking-Driven Discovery of Antibacterial Perinadines, New Tetracyclic Alkaloids from the Marine Sponge-Derived Fungus Aspergillus sp.
Two rare tetracyclic skeleton alkaloids named perinadines B and C (1 and 2) were isolated
as mixtures of epimers from the marine-derived Aspergillus sp. LS116 driven by molecular …
as mixtures of epimers from the marine-derived Aspergillus sp. LS116 driven by molecular …
[HTML][HTML] Anti-SARS-CoV-2 and cytotoxic activity of two marine alkaloids from green alga Caulerpa cylindracea Sonder in the Dardanelles
Caulerpa cylindracea Sonder is a green alga belonging to the Caulerpaceae family. This is
the first chemical investigation of C. cylindracea in the Dardanelles which resulted in the …
the first chemical investigation of C. cylindracea in the Dardanelles which resulted in the …