[HTML][HTML] Short-Term and Sub-Chronic Dietary Exposure to Aspalathin-Enriched Green Rooibos (Aspalathus linearis) Extract Affects Rat Liver Function and Antioxidant …
JD Van der Merwe, D De Beer, E Joubert… - Molecules, 2015 - mdpi.com
An aspalathin-enriched green rooibos (Aspalathus linearis) extract (GRE) was fed to male
Fischer rats in two independent studies for 28 and 90 days. The average dietary total …
Fischer rats in two independent studies for 28 and 90 days. The average dietary total …
[HTML][HTML] Pharmacokinetic interaction of green rooibos extract with atorvastatin and metformin in rats
O Patel, CJF Muller, E Joubert, B Rosenkranz… - Frontiers in …, 2019 - frontiersin.org
An aspalathin-rich green rooibos extract (Afriplex GRT™) has demonstrated anti-diabetic
and hypolipidemic properties, while also moderately inhibiting CYP3A4 activity, suggesting …
and hypolipidemic properties, while also moderately inhibiting CYP3A4 activity, suggesting …
New insights into the trophic and cytoprotective effects of creatine in in vitro and in vivo models of cell maturation
P Sestili, P Ambrogini, E Barbieri, S Sartini… - Amino Acids, 2016 - Springer
A growing body of scientific reports indicates that the role of creatine (Cr) in cellular
biochemistry and physiology goes beyond its contribution to cell energy. Indeed Cr has …
biochemistry and physiology goes beyond its contribution to cell energy. Indeed Cr has …
Long-term administration of Aspalathus linearis infusion affects spatial memory of adult Sprague-Dawley male rats as well as increases their striatal dopamine content
J Pyrzanowska, I Fecka, D Mirowska-Guzel… - Journal of …, 2019 - Elsevier
Ethnopharmacological relevance Everyday use of the herbal tea rooibos, produced from
Aspalathus linearis (Brum. f) Dahlg.(Fabaceae) is customary in South Africa, a continuation …
Aspalathus linearis (Brum. f) Dahlg.(Fabaceae) is customary in South Africa, a continuation …
Conditioned media from human palatine tonsil mesenchymal stem cells regulates the interaction between myotubes and fibroblasts by IL‐1Ra activity
KA Cho, M Park, YH Kim, SY Woo… - Journal of Cellular and …, 2017 - Wiley Online Library
Saturated free fatty acids (FFA s) act as lipid mediators and induce insulin resistance in
skeletal muscle. Specifically, in obesity‐related diseases such as type 2 diabetes, FFA s …
skeletal muscle. Specifically, in obesity‐related diseases such as type 2 diabetes, FFA s …
[HTML][HTML] Translation of preclinical ethnomedicine data in LMICs: the example of rooibos
L Pretorius, C Smith - Frontiers in Pharmacology, 2023 - frontiersin.org
All disease, but especially non-communicable diseases, are related to dysfunction of one or
more regulatory systems. In developing countries, long-term management of patients with …
more regulatory systems. In developing countries, long-term management of patients with …
BPN, a marine-derived PTP1B inhibitor, activates insulin signaling and improves insulin resistance in C2C12 myotubes
Q Xu, J Luo, N Wu, R Zhang, D Shi - International journal of biological …, 2018 - Elsevier
Insulin resistance is a key feature of type 2 diabetes mellitus (T2DM) and is characterized by
defects in insulin signaling. Protein tyrosine phosphatase 1B (PTP1B) is a major negative …
defects in insulin signaling. Protein tyrosine phosphatase 1B (PTP1B) is a major negative …
Pharmacological activity of Aspalathus linearis extracts: pre-clinical research in view of prospective neuroprotection
J Pyrzanowska - Nutritional Neuroscience, 2023 - Taylor & Francis
Objectives Rooibos tea, a very popular everyday beverage made of Aspalathus linearis
plant material and containing multiple polyphenolic compounds, reveals an expectation to …
plant material and containing multiple polyphenolic compounds, reveals an expectation to …
The role of glucose and fatty acid metabolism in the development of insulin resistance in skeletal muscle
SE Mazibuko-Mbeje, PV Dludla… - Muscle cell and …, 2018 - books.google.com
The rapid rise in the prevalence of obesity and diabetes has significantly contributed to the
increasing global burden of noncommunicable diseases. Insulin resistance is a major …
increasing global burden of noncommunicable diseases. Insulin resistance is a major …
Improvement of palmitate-induced insulin resistance in C2C12 skeletal muscle cells using Platycodon grandiflorum seed extracts
HJ Yoon, MH Bang, H Kim, JY Imm - Food Bioscience, 2018 - Elsevier
Platycodon grandiflorum seeds (PGSE) and P. grandiflorum root extracts (PGRE) were
prepared and their effect on glucose uptake were evaluated in C2C12 myotubes. PGSE had …
prepared and their effect on glucose uptake were evaluated in C2C12 myotubes. PGSE had …