Capsicum Waste as a Sustainable Source of Capsaicinoids for Metabolic Diseases
Capsaicinoids are pungent alkaloid compounds enriched with antioxidants, anti-microbial,
anti-inflammatory, analgesics, anti-carcinogenic, anti-obesity and anti-diabetic properties …
anti-inflammatory, analgesics, anti-carcinogenic, anti-obesity and anti-diabetic properties …
In silico drug repurposing framework predicts repaglinide, agomelatine and protokylol as TRPV1 modulators with analgesic activity
Pain is one of the most common symptoms experienced by patients. The use of current
analgesics is limited by low efficacy and important side effects. Transient receptor potential …
analgesics is limited by low efficacy and important side effects. Transient receptor potential …
Drug–Target Interaction Deep Learning-Based Model Identifies the Flavonoid Troxerutin as a Candidate TRPV1 Antagonist
J Lee, H Yoon, YJ Lee, TY Kim, G Bahn, Y Kim… - Applied Sciences, 2023 - mdpi.com
Based on the advances made by artificial intelligence (AI) technologies in drug discovery,
including target identification, hit molecule identification, and lead optimization, this study …
including target identification, hit molecule identification, and lead optimization, this study …
[HTML][HTML] Pivotal roles of TRPV1 channel and Nrf2 factor in green light modulation of keratinocyte inflammatory response
S Salman, S Raccah, A Rousseaud, L Declercq… - … of Photochemistry and …, 2024 - Elsevier
Photobiomodulation (PBM) is emerging as a promising non-invasive approach for managing
inflammatory skin conditions. However, its precise molecular mechanisms, especially within …
inflammatory skin conditions. However, its precise molecular mechanisms, especially within …
Discovery of novel TRPV1 modulators through machine learning‐based molecular docking and molecular similarity searching
X Wei, Q Yang, Z Yang, T Huang… - Chemical Biology & …, 2023 - Wiley Online Library
The transient receptor potential vanilloid 1 (TRPV1) channel belongs to the transient
receptor potential channel superfamily and participates in many physiological processes …
receptor potential channel superfamily and participates in many physiological processes …