Although more common in developing countries, over 11,000 deaths will occur in the United
States from head and neck cancer in 2004. Squamous cell carcinomas account for the vast …

Squamous intraepithelial lesions (SILs) of the larynx, clinically usually defined as
leukoplakia and chronic laryngitis, have remained the main controversial topic in laryngeal …

Objectives The prevalence of gastroesophageal reflux disease (GERD) in patients with
laryngopharyngeal disorders is probably greater than realized. Study Design Prospective …

Laryngopharyngeal reflux (LPR) refers to the backflow of stomach contents into the
laryngopharynx. Increasing evidence has demonstrated that LPR is a contributing factor in …

Abstract Objective/Hypothesis: Laryngopharyngeal reflux (LPR) is thought to be a significant
risk factor for laryngeal squamous cell carcinoma (SCC), but causality has never been …

Hypothesis At present, main factors considered responsible for the onset of squamous cell
carcinoma are tobacco smoking, alcohol abuse, and exposure to viral and toxic agents. In …

OBJECTIVE: To determine the significance of laryngopharyngeal reflux (LPR) in benign
vocal mucosal lesions. STUDY DESIGN AND SETTING: A case-control study at the tertiary …

It has been postulated that gastroesophageal reflux plays a role in the etiology of head and
neck squamous cell carcinomas (HNSCC) and contributes to complications after surgery or …

PURPOSE: Gastroesophageal reflux disease (GERD) is common in patients with laryngeal
cancer. However, the role of GERD in laryngeal cancer remains controversial because of …

BACKGROUND An association between laryngopharyngeal reflux (LPR) and laryngeal
carcinoma has been suggested, but remains unproven. The current pilot study was …