Roadmap: proton therapy physics and biology

H Paganetti, C Beltran, S Both, L Dong… - Physics in Medicine …, 2021 - iopscience.iop.org
The treatment of cancer with proton radiation therapy was first suggested in 1946 followed
by the first treatments in the 1950s. As of 2020, almost 200 000 patients have been treated …

Proton therapy for head and neck squamous cell carcinomas: A review of the physical and clinical challenges

A Beddok, A Vela, V Calugaru, T Tessonnier… - Radiotherapy and …, 2020 - Elsevier
The quality of radiation therapy has been shown to significantly influence the outcomes for
head and neck squamous cell carcinoma (HNSCC) patients. The results of dosimetric …

Head and neck radiotherapy on the MR linac: a multicenter planning challenge amongst MRIdian platform users

M Chamberlain, J Krayenbuehl… - Strahlentherapie und …, 2021 - Springer
Purpose Purpose of this study is to evaluate plan quality on the MRIdian (Viewray Inc.,
Oakwood Village, OH, USA) system for head and neck cancer (HNC) through comparison of …

[HTML][HTML] Fast, automated, knowledge-based treatment planning for selecting patients for proton therapy based on normal tissue complication probabilities

R Hytönen, MR Vergeer, R Vanderstraeten… - Advances in Radiation …, 2022 - Elsevier
Purpose Selecting patients who will benefit from proton therapy is laborious and subjective.
We demonstrate a novel automated solution for creating high-quality knowledge-based …

Dose distribution prediction for head-and-neck cancer radiotherapy using a generative adversarial network: influence of input data

X Gu, VIJ Strijbis, BJ Slotman, MR Dahele… - Frontiers in …, 2023 - frontiersin.org
Purpose A three-dimensional deep generative adversarial network (GAN) was used to
predict dose distributions for locally advanced head and neck cancer radiotherapy. Given …

Automatic segmentation of head and neck primary tumors on MRI using a multi-view CNN

JPE Schouten, S Noteboom, RM Martens, SW Mes… - Cancer Imaging, 2022 - Springer
Background Accurate segmentation of head and neck squamous cell cancer (HNSCC) is
important for radiotherapy treatment planning. Manual segmentation of these tumors is time …

[HTML][HTML] Head and neck radiation therapy patterns of practice variability identified as a challenge to real-world big data: Results from the Learning From Analysis of …

A Caissie, M Mierzwa, CD Fuller, M Rajaraman… - Advances in radiation …, 2023 - Elsevier
Purpose Outside of randomized clinical trials, it is difficult to develop clinically relevant
evidence-based recommendations for radiation therapy (RT) practice guidelines owing to …

Relationship between treatment plan dosimetry, toxicity, and survival following intensity-modulated radiotherapy, with or without chemotherapy, for stage III inoperable …

IF Remmerts de Vries, MI Ronden, I Bahce… - Cancers, 2021 - mdpi.com
Simple Summary Various radiotherapy treatment methods are available for patients with
stage III non-small-cell lung cancer (NSCLC). A multidisciplinary tumor board review is …

[HTML][HTML] Development of advanced preselection tools to reduce redundant plan comparisons in model-based selection of head and neck cancer patients for proton …

M Tambas, HP van der Laan, W Rutgers… - Radiotherapy and …, 2021 - Elsevier
Abstract Purpose In the Netherlands, head and neck cancer (HNC) patients are selected for
proton therapy (PT) based on estimated normal tissue complication probability differences …

Inter-institutional variation in intensity-modulated radiotherapy for breast cancer in Korea (KROG 19-01)

K Kim, M Chun, H Jin, W Jung, KH Shin… - Anticancer …, 2021 - ar.iiarjournals.org
Background/Aim: To present the variations in the target delineation and the planning results
of intensity-modulated radiation therapy (IMRT) for breast cancers. Patients and Methods …