Circular RNAs in neuroblastoma: Pathogenesis, potential biomarker, and therapeutic target
Neuroblastoma (NB) is a common cancer in childhood responsible for 15% of fatalities by
pediatric cancers. Epigenetic factors play an important role in the pathogenesis of NB …
pediatric cancers. Epigenetic factors play an important role in the pathogenesis of NB …
Development and validation of a novel 11-gene prognostic model for serous ovarian carcinomas based on lipid metabolism expression profile
M Zheng, H Mullikin, A Hester, B Czogalla… - International journal of …, 2020 - mdpi.com
(1) Background: Biomarkers might play a significant role in predicting the clinical outcomes
of patients with ovarian cancer. By analyzing lipid metabolism genes, future perspectives …
of patients with ovarian cancer. By analyzing lipid metabolism genes, future perspectives …
The role of omics approaches to characterize molecular mechanisms of rare ovarian cancers: recent advances and future perspectives
Rare ovarian cancers are ovarian cancers with an annual incidence of less than 6 cases per
100,000 women. They generally have a poor prognosis due to being delayed diagnosis and …
100,000 women. They generally have a poor prognosis due to being delayed diagnosis and …
Pharmacological inhibition of lipid import and transport proteins in ovarian Cancer
Simple Summary Ovarian cancer (OC) is still the most lethal gynecological cancer due to
late diagnosis when peritoneal metastasis has already occurred. OC progression requires …
late diagnosis when peritoneal metastasis has already occurred. OC progression requires …
A comprehensive molecular analysis of 113 primary ovarian clear cell carcinomas reveals common therapeutically significant aberrations
I Stružinská, N Hájková, J Hojný, E Krkavcová… - Diagnostic …, 2023 - Springer
Background Molecular aberrations occurring in primary ovarian clear cell carcinoma
(OCCC) can be of diagnostic, predictive, and prognostic significance. However, a complex …
(OCCC) can be of diagnostic, predictive, and prognostic significance. However, a complex …
Membrane disruption, but not metabolic rewiring, is the key mechanism of anticancer-action of FASN-inhibitors: A multi-omics analysis in ovarian cancer
Abstract Fatty-acid (FA)-synthase (FASN) is a druggable lipogenic oncoprotein whose
blockade causes metabolic disruption. Whether drug-induced metabolic perturbation is …
blockade causes metabolic disruption. Whether drug-induced metabolic perturbation is …
The genomic trajectory of ovarian high‐grade serous carcinoma can be observed in STIC lesions
Ovarian high‐grade serous carcinoma (HGSC) originates in the fallopian tube, with
secretory cells carrying a TP53 mutation, known as p53 signatures, identified as potential …
secretory cells carrying a TP53 mutation, known as p53 signatures, identified as potential …
Integrative genomics approach identifies molecular features associated with early-stage ovarian carcinoma histotypes
Ovarian cancer comprises multiple subtypes (clear-cell (CCC), endometrioid (EC), high-
grade serous (HGSC), low-grade serous (LGSC), and mucinous carcinomas (MC)) with …
grade serous (HGSC), low-grade serous (LGSC), and mucinous carcinomas (MC)) with …
Multicellular ovarian cancer model for evaluation of nanovector delivery in ascites and metastatic environments
SJ Winter, HA Miller, JM Steinbach-Rankins - Pharmaceutics, 2021 - mdpi.com
A novel multicellular model composed of epithelial ovarian cancer and fibroblast cells was
developed as an in vitro platform to evaluate nanovector delivery and ultimately aid the …
developed as an in vitro platform to evaluate nanovector delivery and ultimately aid the …
A multi-omics approach to understand the influence of polyphenols in ovarian cancer for precision nutrition: a mini-review
F Tecchio Borsoi, L Ferreira Alves… - Critical Reviews in …, 2023 - Taylor & Francis
The impact of polyphenols in ovarian cancer is widely studied observing gene expression,
epigenetic alterations, and molecular mechanisms based on new 'omics' technologies …
epigenetic alterations, and molecular mechanisms based on new 'omics' technologies …