Dose-dense adjuvant breast cancer chemotherapy is a new treatment strategy that aims to
improve tumour control by using more frequent cytotoxic dosing together with continuous …

Angiogenesis, or formation of new blood capillaries from preexisting vessels, plays both
beneficial and damaging roles in the organism. It is a result of a complex balance of positive …

Inhibiting the angiogenic process is a clever method of cancer care. Over the last decade,
some antiangiogenic compounds have been developed and approved for cancer treatment …

Purpose.: This study was undertaken to determine whether anti-vascular endothelial growth
factor (VEGF) therapy inhibits growth of primary uveal melanoma and spread of its hepatic …

Current treatment modalities for cancer combine cytotoxic drugs against DNA and novel
targeted drugs affecting signal transduction pathways, which are required for growth …

Background: Posterior reversible encephalopathy syndrome (PRES) is a potentially
devastating complication of bevacizumab treatment. Aim: We examined the clinical features …

Vascular endothelial growth factor (VEGF-A) is a key cytokine in the development of normal
blood vessels as well as the development of vessels in tumors and other tissues undergoing …

Secreted Wnt ligands play a major role in the development and progression of many
cancers by modulating signaling through cell-surface Frizzled receptors (FZDs). In order to …

The purpose of this study was to assess the response rate and toxicity of paclitaxel,
carboplatin, and bevacizumab (PCB) primary induction therapy for the treatment of …

Tyrosine kinase inhibitors (TKIs) have revolutionized the prognosis of chronic myeloid
leukemia. With the advent of highly efficacious therapy, the focus has shifted toward …