Anti-angiogenic therapy: Prospects for treatment of ocular tumors
MI Rosenblatt, DT Azar - Seminars in ophthalmology, 2006 - Taylor & Francis
The growth of new blood vessels (angiogenesis) within tumors is essential for tumor growth,
maintenance, and metastasis. Angiogenesis research has identified a host of pro-and anti …
maintenance, and metastasis. Angiogenesis research has identified a host of pro-and anti …
Intraperitoneal bevacizumab combined with cytoreductive surgery: a pre-clinical study of tolerance and pharmacokinetics in an animal model
Abstract Introduction Cytoreductive Surgery (CRS) combined with Hyperthermic
Intraperitoneal Chemotherapy (HIPEC) is currently the only potentially curative treatment for …
Intraperitoneal Chemotherapy (HIPEC) is currently the only potentially curative treatment for …
In vitro the behaviors of metastasis with suppression of VEGF in human bone metastatic LNCaP-derivative C4-2B prostate cancer cell line
L Yang, S You, V Kumar, C Zhang, Y Cao - Journal of Experimental & …, 2012 - Springer
Background Vascular endothelial growth factor (VEGF) is a signal protein produced by cells
that stimulates vasculogenesis and angiogenesis. VEGF is believed to implicate poor …
that stimulates vasculogenesis and angiogenesis. VEGF is believed to implicate poor …
Contemporary use of bevacizumab in ovarian cancer
TM Miyake, AK Sood, RL Coleman - Expert opinion on biological …, 2013 - Taylor & Francis
Introduction: Ovarian cancer remains the most lethal gynecologic malignancy. Although
standard platinum-based chemotherapy results in high response rates, more than 70% of …
standard platinum-based chemotherapy results in high response rates, more than 70% of …
YM-359445, an orally bioavailable vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor, has highly potent antitumor activity against established …
N Amino, Y Ideyama, M Yamano, S Kuromitsu… - Clinical cancer …, 2006 - AACR
Purpose: The vascular endothelial growth factor receptor-2 (VEGFR2) tyrosine kinase has
been implicated in the pathologic angiogenesis associated with tumor growth. YM-359445 …
been implicated in the pathologic angiogenesis associated with tumor growth. YM-359445 …
Anterior chamber paracentesis might prevent sustained intraocular pressure elevation after intravitreal injections of ranibizumab for age-related macular degeneration
Y Ichiyama, T Sawada, M Kakinoki, O Sawada… - Ophthalmic …, 2014 - karger.com
Background/Aims: To evaluate the efficacy of anterior chamber paracentesis for preventing
sustained intraocular pressure (IOP) elevation after intravitreal ranibizumab (IVR) injections …
sustained intraocular pressure (IOP) elevation after intravitreal ranibizumab (IVR) injections …
Photodynamic Therapy–Induced Angiogenic Signaling: Consequences and Solutions to Improve Therapeutic Response
SM Gallagher‐Colombo, AL Maas… - Israel journal of …, 2012 - Wiley Online Library
Photodynamic therapy (PDT) can be a highly effective treatment for diseases ranging from
actinic keratosis to cancer. While use of this therapy shows great promise in preclinical and …
actinic keratosis to cancer. While use of this therapy shows great promise in preclinical and …
Cytotoxicity of VEGF121/rGel on vascular endothelial cells resulting in inhibition of angiogenesis is mediated via VEGFR-2
KA Mohamedali, S Ran, C Gomez-Manzano… - BMC cancer, 2011 - Springer
Background The fusion protein VEGF 121/rGel composed of the growth factor VEGF 121
and the plant toxin gelonin targets the tumor neovasculature and exerts impressive anti …
and the plant toxin gelonin targets the tumor neovasculature and exerts impressive anti …