Highlights•Mitochondrial dynamic and biogenesis are abnormal in white adipose tissue in
this animal model of obesity and type 2 diabetes.•Drp-1 fission protein is overexpressed …

Our understanding of the pathophysiology of obesity remains at best incomplete despite a
century of research. During this time, two alternative perspectives have helped shape …

Metabolic syndrome (MetS) refers to a cluster of metabolic dysregulations, which include
insulin resistance, obesity, atherogenic dyslipidemia and hypertension. The complex …

Chronic intermittent hypoxia (CIH), a pathophysiological manifestation of obstructive sleep
apnea (OSA), is strongly correlated with obesity, as patients with the disease experience …

Obesity is an excessive accumulation or expansion of adipose tissue (AT) due to an
increase in either the size and/or number of its characteristic cell type, the adipocyte. As one …

Aims Leptin/leptin resistance has been suggested to play a role in nonalcoholic fatty liver
disease (NAFLD), and therefore we investigated the correlation of leptin/leptin‐receptor …

The incidence of sarcopenic obesity among adults aged≥ 65 years is rising worldwide.
Sarcopenic obesity is a high‐risk geriatric syndrome defined as a gain in the amount of …

In the healthy state, the fat stored in our body isn't just inert. Rather, it is dynamically
mobilized to maintain an adequate concentration of fatty acids (FAs) in our bloodstream. Our …

Obesity is a worldwide epidemic characterized by excessive fat accumulation, associated
with multiple comorbidities and complications. Emerging evidence points to gut microbiome …

The hormonal fluctuations in pregnancy drive a wide range of adaptive changes in the
maternal brain. These range from specific neurophysiological changes in the patterns of …