Simple Summary Adipocytes or fat cells are integral part of the ovarian tumor
microenvironment. Secreted factors from adipocytes, as well as direct cell-to-cell interaction …

The intramuscular fat (IMF) content and fatty acid composition are important meat quality
traits that are mostly affected by the cattle breed. Muscle, adipose tissue and liver are …

Objectives Low early-life leptin concentrations may promote faster weight gain in infancy.
We aimed to examine the associations between cord blood leptin concentrations and …

Leptin is a cytokine-like hormone that functions as a link between obesity and breast cancer
(BC). Leptin treatment induces Epithelial to Mesenchymal Transition (EMT) in BC cell lines …

Background/objectives Lysyl oxidase (LOX) is an enzyme crucial for collagen fibre
crosslinking and thus for fibrosis development. Fibrosis is characterised by a surplus of …

Cadmium (Cd) is a toxic heavy metal that is widespread in the environment due to the
substantial anthropogenic inputs from the agriculture and industrial sectors. The toxic impact …

Background and aims Although the importance of adipokines in modulating the disease
process of type 2 diabetes is well recognized, there is dearth of data on the specific role of …

BACKGROUND Modern guidelines recommend sodium-glucose cotransporter-2 (SGLT2)
inhibitors as the preferred antihyperglycemic agents for patients with type 2 diabetes and …

Hypothalamic resistance to adipostatic actions of leptin is a hallmark of obesity. Studies
have revealed that hypothalamic inflammation, triggered in response to the consumption of …

Background Maternal diet is an important factor in prenatal development that also has
implications for disease risk later in life. The adipokine leptin is a key regulator of energy …