Retinal ischemia: mechanisms of damage and potential therapeutic strategies
Retinal ischemia is a common cause of visual impairment and blindness. At the cellular
level, ischemic retinal injury consists of a self-reinforcing destructive cascade involving …
level, ischemic retinal injury consists of a self-reinforcing destructive cascade involving …
Mitochondrial KATP channels stabilize intracellular Ca2+ during hypoxia in retinal horizontal cells of goldfish (Carassius auratus)
MW Country, MG Jonz - Journal of Experimental Biology, 2021 - journals.biologists.com
Neurons of the retina require oxygen to survive. In hypoxia, neuronal ATP production is
impaired, ATP-dependent ion pumping is reduced, transmembrane ion gradients are …
impaired, ATP-dependent ion pumping is reduced, transmembrane ion gradients are …
Layer-specific blood-flow MRI of retinitis pigmentosa in RCS rats
The Royal College of Surgeons (RCS) rat is an established animal model of retinitis
pigmentosa, a family of inherited retinal diseases which starts with loss of peripheral vision …
pigmentosa, a family of inherited retinal diseases which starts with loss of peripheral vision …
Protective activity of ischemic preconditioning on rat testicular ischemia: effects of Y-27632 and 5-hydroxydecanoic acid
A Gozen, S Demiryurek, A Taskin, H Ciralik… - Journal of Pediatric …, 2013 - Elsevier
Abstract Background/Purpose The aim of this study was to investigate the role of ischemic
preconditioning (IPC) on ischemia/reperfusion (I/R)-induced injury of rat testis and determine …
preconditioning (IPC) on ischemia/reperfusion (I/R)-induced injury of rat testis and determine …
Post-ischemic conditioning in the rat retina is dependent upon ischemia duration and is not additive with ischemic pre-conditioning
JC Dreixler, AR Shaikh, M Alexander, B Savoie… - Experimental eye …, 2010 - Elsevier
Ischemic pre-conditioning (IPC) provides neuroprotection in the rat retina from the damaging
effects of severe ischemia. Recently, neuroprotection by retinal ischemic post-conditioning …
effects of severe ischemia. Recently, neuroprotection by retinal ischemic post-conditioning …
Neurotoxic effects of local anesthetics on the mouse neuroblastoma NB2a cell line
M Mete, I Aydemir, IM Tuglu… - Biotechnic & …, 2015 - Taylor & Francis
Local anesthetics are used clinically for peripheral nerve blocks, epidural anesthesia, spinal
anesthesia and pain management; large concentrations, continuous application and long …
anesthesia and pain management; large concentrations, continuous application and long …
[HTML][HTML] Environmental damage to the retina and preconditioning: contrasting effects of light and hyperoxic stress
Purpose.: Environmental stress (bright light, hypoxia) can “condition” retinal photoreceptors,
increasing their resistance to subsequent stress. The present study tests whether another …
increasing their resistance to subsequent stress. The present study tests whether another …
Manganese‐enhanced MRI reveals multiple cellular and vascular layers in normal and degenerated retinas
Purpose: To use manganese‐enhanced magnetic resonance imaging (MEMRI) at 25× 25×
800 μm3 to image different retinal and vascular layers in the rat retinas. Materials and …
800 μm3 to image different retinal and vascular layers in the rat retinas. Materials and …
[HTML][HTML] Effect of bacterial lipopolysaccharide on ischemic damage in the rat retina
PJ Franco, DC Fernandez, PH Sande… - … & visual science, 2008 - arvojournals.org
purpose. The purpose of this study was to investigate whether bacterial lipopolysaccharide
(LPS) induces ischemic preconditioning in the rat retina, and, if so, whether nitric oxide (NO) …
(LPS) induces ischemic preconditioning in the rat retina, and, if so, whether nitric oxide (NO) …
[HTML][HTML] The protective effect of ischemic preconditioning on rat testis
Background It has been demonstrated that brief episodes of sublethal ischemia-reperfusion,
so-called ischemic preconditioning, provide powerful tissue protection in different tissues …
so-called ischemic preconditioning, provide powerful tissue protection in different tissues …