Fixed combination for the treatment of dyslipidaemia
Abstract Purpose of Review It is clear from epidemiological studies that patients at high and
very-high risk of atherosclerotic cardiovascular diseases (ASCVD) risk do not reach lipid …
very-high risk of atherosclerotic cardiovascular diseases (ASCVD) risk do not reach lipid …
A new approach of statin therapy in carotid atherosclerosis: Targeting indices of plaque vulnerability on the top of lipid-lowering. A narrative review
NPE Kadoglou, E Khattab, N Velidakis… - Polish Heart …, 2022 - journals.viamedica.pl
Novel imaging techniques and biomarkers have emerged as surrogate markers of carotid
plaque vulnerability. In parallel, statin administration in patients with established carotid …
plaque vulnerability. In parallel, statin administration in patients with established carotid …
Effect of high-dose statin therapy on coagulation factors: lowering of factor XI as a modifier of fibrin clot properties in coronary artery disease
Background Multiple pleiotropic effects of statins include antithrombotic properties with
formation of looser fibrin networks more susceptible to lysis. Recently, rosuvastatin 20 mg/d …
formation of looser fibrin networks more susceptible to lysis. Recently, rosuvastatin 20 mg/d …
Green electrochemical methodology for simultaneous determination of atorvastatin and ezetimibe: Application to biological matrices
SA Atty, AM Abdel-raoof, FA Fouad… - Sustainable Chemistry …, 2023 - Elsevier
In this context, we report the first electrochemical sensing platform for the simultaneous
quantitation of two antihyperlipidemic drugs, namely, atorvastatin (ATR) and ezetimibe …
quantitation of two antihyperlipidemic drugs, namely, atorvastatin (ATR) and ezetimibe …
Low-density lipoprotein cholesterol-lowering drugs: a narrative review
N Ferri, M Ruscica, S Fazio, A Corsini - Journal of Clinical Medicine, 2024 - mdpi.com
The modern history of cholesterol-lowering drugs started in 1972 when Dr. Akira Endo
identified an active compound (compactin) that inhibited cholesterol biosynthesis from the …
identified an active compound (compactin) that inhibited cholesterol biosynthesis from the …
Implication of lipids in calcified aortic valve pathogenesis: why did statins fail?
MJ Nsaibia, A Devendran, E Goubaa, J Bouitbir… - Journal of Clinical …, 2022 - mdpi.com
Calcific Aortic Valve Disease (CAVD) is a fibrocalcific disease. Lipoproteins and oxidized
phospholipids play a substantial role in CAVD; the level of Lp (a) has been shown to …
phospholipids play a substantial role in CAVD; the level of Lp (a) has been shown to …
Prognostic value of the triglyceride-glucose index among non-diabetic patients with acute myocardial infarction at one-year follow-up
Background: The triglyceride-glucose index (TyG index) is a novel metabolic marker initially
used as an indicator of insulin resistance. Recently, its use as a cardiovascular risk factor …
used as an indicator of insulin resistance. Recently, its use as a cardiovascular risk factor …
Towards personalized therapy of aortic stenosis
P Mazur, M Kopytek, M Ząbczyk, A Undas… - Journal of Personalized …, 2021 - mdpi.com
Calcific aortic stenosis (CAS) is the most common cause of acquired valvular heart disease
in adults with no available pharmacological treatment to inhibit the disease progression to …
in adults with no available pharmacological treatment to inhibit the disease progression to …
Aortic valvular stenosis: Novel therapeutic strategies
J Natorska, M Kopytek, A Undas - European Journal of Clinical …, 2021 - Wiley Online Library
Background Aortic stenosis (AS) prevalence is estimated to reach 4.5 million cases
worldwide by the year 2030. AS is a progressive disease without a pharmacological …
worldwide by the year 2030. AS is a progressive disease without a pharmacological …
Therapy with high-dose statins reduces soluble P-selectin: The impact on plasma fibrin clot properties
J Siudut, J Pudło, M Konieczyńska, M Polak… - International Journal of …, 2023 - Elsevier
Objective Studies on the effect of statins on platelets in patients with coronary artery disease
(CAD) yielded inconsistent results. We sought to investigate whether high-dose statin …
(CAD) yielded inconsistent results. We sought to investigate whether high-dose statin …