Studi In Silico Potensi Piperine, Piperlongumine, dan Thymoquinone Sebagai Obat Alzheimer
Alzheimer's disease (AD) was suffered by 30-35 million patients worldwide and predicted to
increase to 400% within 30 years in Indonesia. One of the accepted therapeutics for AD is …
increase to 400% within 30 years in Indonesia. One of the accepted therapeutics for AD is …
Novel missense alleles of SIGMAR1 as tools to understand emerin-dependent gene silencing in response to cocaine
AS Arun, CR Eddings… - Experimental Biology and …, 2019 - journals.sagepub.com
Sigma-1 receptor (Sigma1R; SIGMAR1), an integral membrane protein of the endoplasmic
reticulum and nuclear envelope, has a hydrophobic drug-binding pocket that binds with high …
reticulum and nuclear envelope, has a hydrophobic drug-binding pocket that binds with high …
Анализ связывающей способности сигма-1 рецепторов при эмоционально-стрессовом воздействии и введении анксиолитика афобазола
ЕВ Абрамова, МВ Воронин… - Химико …, 2019 - chem.folium.ru
Аннотация Специфическое связывание лиганда сигма-1 рецепторов (Sigma1R)[3 H](+)-
пентазоцина в Р2 и Р3 фракциях гомогенатов головного мозга определяли у …
пентазоцина в Р2 и Р3 фракциях гомогенатов головного мозга определяли у …
Афобазол ослабляет когнитивную ригидность в экспериментальной модели расстройств аутистического спектра
ИГ Капица, АП Калинина, АА Алымов… - … биологии и медицины, 2019 - elibrary.ru
На фенотипической модели расстройств аутистического спектра-мышах линии BALB/c-
показано, что афобазол в дозе 10 мг/кг уменьшает когнитивную ригидность. Афобазол …
показано, что афобазол в дозе 10 мг/кг уменьшает когнитивную ригидность. Афобазол …
IP3R at ER-mitochondrial contact sites: beyond the IP3R-GRP75-VDAC1 Ca2+ funnel
P Atakba - 2023 - repository.cam.ac.uk
Membrane contact sites (MCS) circumvent the topological constraints of functional coupling
between different membrane-bound organelles by providing a means of communication and …
between different membrane-bound organelles by providing a means of communication and …
[图书][B] Structure Activity Relationship (SAR) Studies of 1, 2-Diarylethylamines as N-Methyl-D-Aspartate Receptor Antagonists
MB Dybek - 2023 - search.proquest.com
Memantine, an N-methyl-D-aspartate receptor (NMDAR) antagonist is FDA approved for the
treatment of moderate to severe Alzheimer disease. The efficacy is believed to stem from its …
treatment of moderate to severe Alzheimer disease. The efficacy is believed to stem from its …
[HTML][HTML] Acupuncture treatment for patients with mild, moderate and severe Alzheimer's disease
B Ji, G Zhao, B Li, Y Liu, N Han, Y Ge… - Longhua Chinese …, 2022 - lcm.amegroups.org
AD, also known as senile dementia, is a neurodegenerative disease characterized by latent
onset and progressive cognitive impairment. The main manifestations are memory and …
onset and progressive cognitive impairment. The main manifestations are memory and …
[图书][B] Sigma Ligand-Mediated Cytosolic Calcium Modulation in BV2 Cells
E Lodholz - 2022 - search.proquest.com
Neuroinflammation is an intricate process of the brain that naturally protects it from
pathogens, foreign bodies, or cellular debris. While initially protective, prolonged …
pathogens, foreign bodies, or cellular debris. While initially protective, prolonged …
[PDF][PDF] The Emerging Role of Sigma Receptors in Pain Medicine
R Raffa, J Pergolizzi Jr, G Varrassi - assets.cureus.com
The first sigma receptor was discovered in 1976 but was erroneously considered another
subtype of opioid receptor. It was later recognized as a protein chaperone with the …
subtype of opioid receptor. It was later recognized as a protein chaperone with the …