Human umbilical vein endothelial cells have recently been shown to respond to C5a with
increases in intracellular Ca2+, production of D-myo-inositol 1, 4, 5-triphosphate and …

NF-κB is a central transcriptional factor and a pleiotropic regulator of many genes involved in
immunological responses. During the screening of a plant extract library of traditional …

The endothelial glycocalyx is a specialized extracellular matrix that covers the apical side of
vascular endothelial cells, projecting into the lumen of blood vessels. The composition of the …

Vascular cell adhesion molecule-1 (VCAM-1) was first identified as a protein that appears on
the surface of endothelial cells after exposure to inflammatory cytokines. Through interaction …

Slit is a secreted protein known to function through the Roundabout (Robo) receptor as a
chemorepellent in axon guidance and neuronal migration, and as an inhibitor in leukocyte …

The chemokine SDF-1 plays a central role in the repopulation of the bone marrow (BM) by
circulating CD34+ progenitors, but the mechanisms of its action remain obscure. To …

Abstract P-selectin (CD62P) is a Ca2+-dependent endogenous lectin that can be expressed
by vascular endothelium and platelets. The major ligand for P-selectin on leukocytes is P …

The selectins are calcium-dependent C-type lectins that bind certain sialylated, fucosylated,
sulfated glycoprotein ligands. L-selectin also recognizes endothelial proteoglycans in a …

Immunohistochemistry of human atherosclerotic arteries demonstrates expression of the
intercellular adhesion molecule-1 (ICAM-1) on endothelial cells, macrophages, and smooth …

P-selectin (CD62, GMP-140, PADGEM), a Ca (2+)-dependent lectin on activated platelets
and endothelium, functions as a receptor for myeloid cells by interacting with sialylated …