Summary The Initial rolling Interaction of leukocytes with the blood vessel wall during
leukocyte trafficking has been postulated to rely on members of the selectin family of …

Much information has been obtained regarding how white cells are recruited in the
microcirculation to sites of inflammation. In this review we summarize the leukocyte …

P-selectin is an endothelial cell adhesion molecule which mediates the binding of
neutrophils and monocytes. Its appearance at the cell surface can be induced within minutes …

The multistep model of leukocyte recruitment to sites of inflammation has helped elucidate
specific molecular cues for each of the individual steps. However, it is less clear how cells …

Adhesion of circulating leukocytes to the vascular endothelium during inflammation is
mediated in part by their Interaction with the endothellal-leukocyte adhesion molecule ELAM …

Endothelial surface expression of P-selectin and subsequent leukocyte rolling in venules
can be induced by mast cell-derived histamine and binding of thrombin to protease …

Particulate air pollution is associated with cardiorespiratory effects and ultrafine particles
(UFPs, diameter< 100 nm) are believed to play an important role. We studied the acute (1 h) …

Cutaneous small-vessel vasculitis (CSVV) refers to a group of disorders usually
characterized by palpable purpura; it is caused by leukocytoclastic vasculitis of postcapillary …

A novel technique involving radiolabeled monoclonal antibodies was used to characterize
and compare the expression of E-and P-selectin on unstimulated, histamine-challenged …

During acute inflammation, P-selectin is transiently mobilized from Weibel-Palade bodies to
the surface of histamine-activated endothelial cells, where it mediates rolling adhesion of …