Intracerebral haemorrhage

L Puy, AR Parry-Jones, EC Sandset… - Nature Reviews …, 2023 - nature.com
Intracerebral haemorrhage (ICH) is a dramatic condition caused by the rupture of a cerebral
vessel and the entry of blood into the brain parenchyma. ICH is a major contributor to stroke …

Neutrophil-to-lymphocyte ratio in acute cerebral hemorrhage: a system review

S Lattanzi, F Brigo, E Trinka, C Cagnetti… - Translational stroke …, 2019 - Springer
Spontaneous intracerebral hemorrhage (ICH) accounts for approximately 10 to 30% of all
acute cerebrovascular events, and it is the type of stroke associated with the highest rates of …

TREM2 activation attenuates neuroinflammation and neuronal apoptosis via PI3K/Akt pathway after intracerebral hemorrhage in mice

S Chen, J Peng, P Sherchan, Y Ma, S Xiang… - Journal of …, 2020 - Springer
Background Neuroinflammation is an important host defense response to secondary brain
injury after intracerebral hemorrhage (ICH). Triggering receptor expressed on myeloid cells …

Brain transforms natural killer cells that exacerbate brain edema after intracerebral hemorrhage

Z Li, M Li, SX Shi, N Yao, X Cheng, A Guo… - Journal of Experimental …, 2020 - rupress.org
Perihematomal edema (PHE) occurs within hours after intracerebral hemorrhage (ICH),
leading to secondary injury manifested by impaired blood–brain barrier (BBB) integrity and …

Neutrophil-to-lymphocyte ratio improves outcome prediction of acute intracerebral hemorrhage

S Lattanzi, C Cagnetti, C Rinaldi, S Angelocola… - Journal of the …, 2018 - Elsevier
Background The inflammatory response plays a role in determining the course of intra-
cerebral hemorrhage (ICH) and immune parameters may have prognostic value. The aim of …

The critical care management of spontaneous intracranial hemorrhage: a contemporary review

AL de Oliveira Manoel, A Goffi, FG Zampieri… - Critical Care, 2016 - Springer
Spontaneous intracerebral hemorrhage (ICH), defined as nontraumatic bleeding into the
brain parenchyma, is the second most common subtype of stroke, with 5.3 million cases and …

Brain‐derived neurotrophic factor and its potential therapeutic role in stroke comorbidities

W Liu, X Wang, M O'Connor, G Wang, F Han - Neural plasticity, 2020 - Wiley Online Library
With the rise in the aging global population, stroke comorbidities have become a serious
health threat and a tremendous economic burden on human society. Current therapeutic …

Neutrophils in traumatic brain injury (TBI): friend or foe?

YW Liu, S Li, SS Dai - Journal of neuroinflammation, 2018 - Springer
Our knowledge of the pathophysiology about traumatic brain injury (TBI) is still limited.
Neutrophils, as the most abundant leukocytes in circulation and the first-line transmigrated …

Pathophysiological mechanisms and potential therapeutic targets in intracerebral hemorrhage

Z Shao, S Tu, A Shao - Frontiers in pharmacology, 2019 - frontiersin.org
Intracerebral hemorrhage (ICH) is a subtype of hemorrhagic stroke with high mortality and
morbidity. The resulting hematoma within brain parenchyma induces a series of adverse …

Role of ferroptosis in neurological diseases

MY Yao, T Liu, L Zhang, MJ Wang, Y Yang, J Gao - Neuroscience Letters, 2021 - Elsevier
Ferroptosis is a newly identified form of nonapoptotic regulated cell death (RCD)
characterized by iron-dependent accumulation of lipid peroxides which leads to oxidative …