Impact of anxiety on prefrontal cortex encoding of cognitive flexibility

J Park, B Moghaddam - Neuroscience, 2017 - Elsevier
Anxiety often is studied as a stand-alone construct in laboratory models. But in the context of
coping with real-life anxiety, its negative impacts extend beyond aversive feelings and …

Making decisions under ambiguity: judgment bias tasks for assessing emotional state in animals

S Roelofs, H Boleij, RE Nordquist… - Frontiers in behavioral …, 2016 - frontiersin.org
Judgment bias tasks (JBTs) are considered as a family of promising tools in the assessment
of emotional states of animals. JBTs provide a cognitive measure of optimism and/or …

Translational assessment of reward and motivational deficits in psychiatric disorders

A Der-Avakian, SA Barnes, A Markou… - Translational …, 2016 - Springer
Deficits in reward and motivation are common symptoms characterizing several psychiatric
and neurological disorders. Such deficits may include anhedonia, defined as loss of …

Modelling cognitive affective biases in major depressive disorder using rodents

CA Hales, SA Stuart, MH Anderson… - British journal of …, 2014 - Wiley Online Library
Major depressive disorder (MDD) affects more than 10% of the population, although our
understanding of the underlying aetiology of the disease and how antidepressant drugs act …

[HTML][HTML] Pharmacological manipulations of judgement bias: A systematic review and meta-analysis

V Neville, S Nakagawa, J Zidar, ES Paul… - Neuroscience & …, 2020 - Elsevier
Validated measures of animal affect are crucial to research spanning numerous disciplines.
Judgement bias, which assesses decision-making under ambiguity, is a promising measure …

Assessment of reward responsiveness in the response bias probabilistic reward task in rats: implications for cross-species translational research

A Der-Avakian, MS D'Souza, DA Pizzagalli… - Translational …, 2013 - nature.com
Mood disorders, such as major depressive disorder, are characterized by abnormal reward
responsiveness. The Response Bias Probabilistic Reward Task (hereafter referred to as …

Rodent tests of depression and anxiety: Construct validity and translational relevance

S Gencturk, G Unal - Cognitive, Affective, & Behavioral Neuroscience, 2024 - Springer
Behavioral testing constitutes the primary method to measure the emotional states of
nonhuman animals in preclinical research. Emerging as the characteristic tool of the …

Translating a rodent measure of negative bias into humans: the impact of induced anxiety and unmedicated mood and anxiety disorders

J Aylward, C Hales, E Robinson… - Psychological …, 2020 - cambridge.org
BackgroundMood and anxiety disorders are ubiquitous but current treatment options are
ineffective for many sufferers. Moreover, a number of promising pre-clinical interventions …

Do horses with poor welfare show 'pessimistic'cognitive biases?

S Henry, C Fureix, R Rowberry, M Bateson… - The Science of …, 2017 - Springer
This field study tested the hypothesis that domestic horses living under putatively
challenging-to-welfare conditions (for example involving social, spatial, feeding constraints) …

The A to Z of statistics for testing cognitive judgement bias.

L Gygax - Animal Behaviour, 2014 - psycnet.apa.org
Abstract Since Harding, Paul, and Mendl's (2004) seminal paper, a nonverbal paradigm for
testing cognitive judgement bias has been applied to assess affective states of a variety of …